Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · May 2007
[Effects of granulocyte-macrophage colony stimulating factor on nuclear factor-KappaB activation in multiple organs of hemorrhage-induced acute lung injury in mice].
To investigate the effects of nuclear factor-KappaB (NF-KappaB) activation in multiple organs of hemorrhage-induced acute lung injury (ALI) by the specific granulocyte-macrophage colony stimulating factor (GM-CSF)-neutralizing antibody (22E9) and dexamethasone (DEX) in mice. ⋯ 22E9 can inhibit the NF-KappaB activation and inflammatory reaction in multiple organs after hemorrhage-induced ALI and reduce injury in multiple organs, while DEX has no significant effect.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · May 2007
[Studies on the temporal profile of expression and release of major pro-inflammatory cytokines in vital organs following hemorrhagic shock].
To study the kinetics of expression and release of major pro-inflammatory cytokines in the vital organs after hemorrhagic shock. ⋯ There is gut-liver-lung axis in the kinetics of expression and release of major pro-inflammatory cytokines after hemorrhagic shock.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Apr 2007
[Effects of 7-nitroindazole on smoke inhalation pulmonary injury].
To investigate the effects of neuronal nitric oxide synthase (nNOS) inhibitor 7-nitroindazole (7-NI) on smoke inhalation pulmonary injury in rats. ⋯ 7-NI shows a good protective effect on smoke inhalation pulmonary injury, that it can raise PaO(2), increase the antioxidation ability, ameliorate lung edema and tissue inflammatory cells infiltration.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Apr 2007
[Effects of L. lactis recombinant heme oxygenase-1 gene on the intestinal barrier in rats with hemorrhagic shock].
To evaluate the effect of gavage of L. lactis recombinant heme oxygenase-1 (HO-1) gene on protection of the intestinal mucosa and the inflammation of lower intestine during hemorrhagic shock. ⋯ The L. lactis recombinant HO-1 has the virtue to deliver HO-1 activity in rats with hemorrhagic shock, which is beneficial for the maintenance of intestinal barrier and anti-inflammation response of the lower intestine.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Apr 2007
[Epidemiological investigation on acute respiratory distress syndrome occurring in intensive care units in Beijing from 1998 to 2003].
To investigate incidence, causes and mortality of acute respiratory distress syndrome (ARDS) in intensive care units (ICU) in Beijing. ⋯ ARDS was frequent in ICU in Beijing, the mortality remains high, and there is no tendency to decline in recent years.