Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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To study the effect of growth hormone (GH) on acute lung injury (ALI) induced by endotoxemia, and its potential therapeutic mechanism. ⋯ The application of GH during early stage of endotoxin challenge can deteriorate the lung injury induced by LPS through enhancing the expression and activation of NF-kappaB, thus enhances the inflammatory response in lungs.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2005
Randomized Controlled Trial Comparative Study[Clinical comparative study of airway pressure release ventilation and continuous positive airway pressure ventilation].
To evaluate the effects of airway pressure release ventilation (APRV) and continuous positive airway pressure (CPAP) on hemodynamics, lung mechanics and oxygen metabolism index. ⋯ In APRV group sedation can be abstained during RM, and the hemodynamics were hardly disturbed. Improvement of lung mechanics and oxygenation is much better with APRV than CPAP mode.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2005
[Dynamic changes in airway hyperresponsiveness as a result of allergen and therapeutic effects of budesonide in rats].
To investigate the dynamic changes in airway hyperresponsiveness (AHR) in allergen-induced asthma in rats and the effects of budesonide. ⋯ (1) Airway hyperresponsiveness increases greatly in mice challenged and sensitized with OVA, and it lasts for about 7 days and then declines afterwards. (2) Budesonide aerosol could effectively alleviate the eosinophil dominant inflammatory response and decrease AHR in the murine asthma model.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2005
Comparative Study[Role of prone position mechanical ventilation in patients with acute respiratory distress syndrome originating from pulmonary disease and extra-pulmonary disease].
To assess the effect of mechanical ventilation on prone position for the treatment of acute respiratory distress syndrome (ARDS) originating from pulmonary disease and extra-pulmonary disease. ⋯ Oxygenation is improved markedly in prone position in two groups. Mechanical ventilation on prone position was an effective method in the treatment of ARDS patients.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2005
[Study of small dural window exposure strategy for preventing intraoperative acute brain herniation during removal of huge intracranial meningiomas].
To investigate and assess the value of small dural window exposure strategy on preventing brain herniation during the operation for huge intracranial meningiomas. ⋯ The small dural window exposure strategy can guarantee safe total removal of huge intracranial meningiomas avoiding the risk of acute intraoperative brain swelling and herniation. Peritumorous brain tissue can be kept intact. Preoperative spinal drainage of cerebrospinal fluid for lowering intracranial pressure is unnecessary in the majority of such cases. Some new knowledge for our understanding the etiological mechanisms and the mechanisms of the surgical strategy to avoid acute intraoperative brain swelling and herniation in removal of huge intracranial meningiomas can be learned.