Polskie Archiwum Medycyny Wewnętrznej
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Pol. Arch. Med. Wewn. · Apr 2022
Sex differences in incidence, management, and outcomes in adult patients aged over 20 years with clinically diagnosed myocarditis in the last ten years: data from the MYO-PL nationwide database.
Comprehensive epidemiological data about the course of myocarditis and sex differ-ences are lacking. ⋯ The incidence of myocarditis was age-, sex-, and season‑dependent. Significant improve-ment is required in the management of myocarditis, including the initial diagnostic process, as well as short-and long‑term therapy, particularly in women.
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Pol. Arch. Med. Wewn. · Apr 2022
Adjuvant combined therapy with trastuzumab in patients with HER2-positive breast cancer and cardiac alterations: implications for optimal cardio-oncology care.
Recently, the prognosis of patients with HER2‑positive breast cancer (BC) has improved significantly owing to the use of combined treatment modalities. However, systemic treatment is as-sociated with increased risk of cardiotoxicity. ⋯ Asymptomatic subclinical cardiac alterations during TT may predict late cardiac complica-tions; however, longer follow‑up is necessary to confirm this hypothesis. Patients with HER2‑positive BC should be closely monitored for possible cardiac alterations during and after therapy to ensure optimal care and guide therapeutic decision‑making.