Polskie Archiwum Medycyny Wewnętrznej
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Pol. Arch. Med. Wewn. · Feb 2023
Applicability of shear wave elastography for lacrimal gland evaluation in primary Sjögren's syndrome.
Primary Sjögren syndrome (pSS) is a systemic autoimmune disease that mainly affects the salivary and lacrimal glands, leading to their progressive destruction. ⋯ SWE of the lacrimal glands is a noninvasive, quantitative method that seems to be a reliable additional examination tool to support the diagnosis of pSS. Its role among the functional tests has not yet been well defined. To confirm the usefulness of SWE for pSS diagnosis, a standardized and widely accepted study protocol should be defined first.
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Pol. Arch. Med. Wewn. · Feb 2023
Pulmonary fibrosis in primary Sjögren's syndrome: computed tomography, clinical features, and associated clinical factors.
Interstitial lung disease (ILD) is common in patients with primary Sjögren syndrome (pSS). Pulmonary fibrosis significantly reduces the patient's quality of life. Therefore, better understanding of the characteristics of patients with pulmonary fibrosis is necessary. ⋯ The presence of dry cough and shortness of breath in the patients with pSS may indicate concomitant pulmonary fibrosis. High‑resolution chest CT can be used for better insights on the occurrence and severity of pulmonary fibrosis in these patients.
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Pol. Arch. Med. Wewn. · Feb 2023
A deep learning model to identify fluid overload status in critically ill patients based on chest X-ray images.
Recent studies have highlighted adverse outcomes of fluid overload in critically ill patients. Therefore, its early recognition is essential for the management of these patients. ⋯ As CXR is routinely used in the intensive care unit, a simple, fast, low‑cost, and noninvasive DL model based on this modality can be regarded as an effective supplementary tool for identifying fluid overload, and should be widely adopted in the clinical setting, especially when invasive hemodynamic monitoring is not available.
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Pol. Arch. Med. Wewn. · Feb 2023
Associations of ANGPTL6, DOCK6, FABP1, and PCSK9 single nucleotide variants and hypercholesterolemia in the Polish population: a cross-sectional study.
Hypercholesterolemia is a chronic noncommunicable disease predisposing to cardiovascular diseases. Genome‑wide association studies have shown that more than 500 common nucleotide variants are associated with dyslipidemia. ⋯ FABP1 rs2919872 and ANGPTL6 rs8112063 are associated with a risk of hypercholesterolemia in the Polish population.