Polskie Archiwum Medycyny Wewnętrznej
-
Pol. Arch. Med. Wewn. · Jan 2025
The role of lipoprotein(a) in atrial fibrillation: a systematic review.
Atrial fibrillation (AF) is the most prevalent form of cardiac arrhythmia worldwide. Early diagnosis and treatment are essential, emphasizing the need to develop novel biomarkers. Lipoprotein(a) [Lp(a)] has recently been widely investigated as a potential risk factor for various cardiovascular conditions, including AF. ⋯ Existing evidence suggests Lp(a) may play a pathophysiological role in AF patients, especially among patients who experience thromboembolic events. Nevertheless, this field requires further research due to inconsistencies in the existing evidence.
-
Pol. Arch. Med. Wewn. · Jan 2025
Clinical characteristics and outcomes of young patients with acute myocardial infarction: YAMI registry.
Despite its low prevalence, premature myocardial infarction (MI) bears serious social consequences and shares different pathophysiology. ⋯ Young MI patients have favorable prognosis and frequently have atypical MI pathophysiology. Cardiac rehabilitation is of utmost importance in mortality reduction regardless of age.
-
Pol. Arch. Med. Wewn. · Jan 2025
Comparison of models predicting efficacy of radioiodine therapy in patients with differentiated thyroid cancer.
Differentiated thyroid cancer (DTC) is the most common type of endocrine malignancy, with rising incidence over recent decades. Despite a favorable prognosis, DTC management remains complex, often involving thyroidectomy followed by radioactive iodine (RAI) therapy. While RAI is crucial for patient outcomes, its efficacy varies, necessitating the identification of predictors for treatment response. ⋯ Our study underscores the utility of sTg as a single parameter for predicting RAI efficacy in DTC patients, with a defined cut-off value facilitating clinical decision-making. The inclusion of CLT status may further enhance predictive models. There is a need to advance personalized management approaches for DTC patients undergoing RAI therapy.
-
Pol. Arch. Med. Wewn. · Jan 2025
Assessment of regional cerebral oxygen saturation and ETCO2 in prediction of the return of spontaneous circulation and patients outcome after in-hospital cardiac arrest.
Cerebral oximetry measurement using near-infrared spectroscopy (NIRS) has been highlighted as a technology that can provide noninvasive information on regional cerebral oxygen saturation (rSO2) during CPR even though its effectiveness has not been fully confirmed. The research focuses on the use of NIRS to predict the return of spontaneous circulation (ROSC) and neurological outcomes. ⋯ The rSO2 value is a more sensitive indicator of ROSC compared to ETCO2. Higher rSO2 values are associated with a higher probability of achieving ROSC. The monitoring of rSO2 during CPR provides prognostic information.
-
Pol. Arch. Med. Wewn. · Jan 2025
Diverticular inflammation and complication assessment does not predict diverticulitis in asymptomatic individuals.
Recently, a three-step endoscopic scale, known as the Diverticular Inflammation and Complication Assessment (DICA), was introduced to predict the course of diverticular disease (DD), yielding some promising outcomes. However, analyses were performed only for symptomatic individuals. ⋯ In our cohort, DICA scale had no predictive value for the occurrence of diverticulitis. Hence, has a limited predictive value for occurrence of diverticulitis and more studies on bigger cohorts are necessary to test its usefulness.