Zhonghua zhong liu za zhi [Chinese journal of oncology]
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Zhonghua Zhong Liu Za Zhi · Aug 2007
[Evaluation of lymph node metastasis in the contralateral mediastinum or scalene through mediastinoscopy and para-mediastinal small incision in potentially operable non-small cell lung cancer].
The purpose of this study was to investigate the clinical characteristics of lymph node metastasis in the contralateral mediastinum and scalene in patients with potentially operable nonsmall cell lung cancer (NSCLC). ⋯ Biopsy of contralateral mediastinal lymph nodes or scalene lymph node should be performed in order to exclude N3 disease for potentially operable NSCLC patients with adenocarcinoma, serum CEA >5 ng/ml or ipsilateral multi-station mediastinal lymph node metastasis.
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Zhonghua Zhong Liu Za Zhi · Jul 2007
[CDK1 expression and effects of CDK1 silencing on the malignant phenotype of glioma cells].
Our previous cDNA array data have shown that expression level of CDK1 increased along with the malignant progression of ganglioglioma, and decreased with the differentiation process of neural stem cells. The purpose of this study was to investigate the CDK1 expression levels in gliomas and the effects of CDK1 knockdown on phenotype of glioma cells. ⋯ Overexpression of CDK1 may promote oncogenesis and progression of human gliomas. Downregulation of CDK1 expression can inhibit the proliferation activities of human malignant gliomas.
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Zhonghua Zhong Liu Za Zhi · Jul 2007
[Whole brain irradiation for non-small-cell lung cancer with brain metastasis].
To investigate the time of whole brain irradiation and the prognostic factors for non-small lung cancer patients with brain metastasis. ⋯ The extracranial metastasis in non-small cell lung cancer patients with brain metastasis is an independent prognostic factors. Early whole brain irradiation may improve the survival for those with brain metastasis symptoms.
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Zhonghua Zhong Liu Za Zhi · Apr 2007
[A case-control study on genetic polymorphism of CYP17 MspA(1)I and its association with endometrial cancer risk].
To assess whether the polymorphisms of CYP17 MspA(1)I are associated with the susceptibility of endometrial cancer. ⋯ No significant relationship was found between CYP17 MspA(1)I genotypes and endometrial cancer risk.
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Zhonghua Zhong Liu Za Zhi · Mar 2007
[Performance of 18F-FDG PET/CT in the detection of primary breast cancer and staging of the regional lymph nodes].
To evaluate the performance of 18F-FDG PET/CT in the detection of primary breast cancer, and the staging of regional lymph nodes. ⋯ As a noninvasive technique, FDG PET/CT appears to be a useful method in staging patient with breast cancer, especially in cases in which the lesion is hard to predict by routine examination. But the accuracy of FDG PET/CT seems to be not high enough to identify patients who might avoid axillary lymph nodes dissection. In the detection of breast lesions, PET/CT doesn't seem to have a high sensitivity, especially in early stage breast cancers. The high cost and the space resolution limit its use as a routine diagnostic method of breast cancer.