MMW Fortschritte der Medizin
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MMW Fortschr Med
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Cases of life-threatening and fatal anaphylaxis represent the most extreme forms of acute allergic reactions. They are estimated to have an incidence of 1-3 per 10,000 persons, with an associated death rate of 0.5-2%. Medicinal drugs, insect stings and foods are the most common triggering agents. ⋯ Fatal anaphylaxis due to foods usually leads first to dyspnea and then to respiratory failure. Allergic bronchial asthma represents a major risk factor. Knowledge of the allergens capable of triggering life-threatening and fatal anaphylaxis makes it easier for the physician to assess the risk potential when confronted by an emergency situation.