Regional anesthesia
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Regional anesthesia · Jul 1994
Comment Letter Case ReportsSevere deformation of a 25-gauge Whitacre spinal needle.
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Regional anesthesia · Jul 1994
Randomized Controlled Trial Clinical TrialSubjective experiences of anesthesiologists undergoing epidural anesthesia.
This study reports subjective experiences of nine anesthesiologists undergoing three consecutive epidural anesthetics. ⋯ All volunteers stated that they would change their anesthetic practice as a result of participation in this study. They believed that having experienced an epidural anesthetic made them better qualified to prepare patients for this anesthetic technique.
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Regional anesthesia · Jul 1994
Comparative StudyProlonged analgesia with liposomal bupivacaine in a mouse model.
Currently available local anesthetics have relatively limited duration of action and some may cause severe systemic toxicity. An ultralong lasting local anesthetic would be useful to produce prolonged intraoperative anesthesia and extended postoperative analgesia. The goal of this study was to synthesize a sustained release local anesthetic formulation that would produce prolonged sensory block and decrease the possibility of systemic toxicity. ⋯ This study shows that liposomal encapsulation of bupivacaine significantly prolongs duration of action and greatly decreases systemic toxicity of the drug. These findings may be promising for the future production of formulations of ultralong lasting local anesthetics with enhanced efficacy and safety.
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Regional anesthesia · Jul 1994
Clinical TrialSubarachnoid microcatheter anesthesia in small children.
Standard single dose spinal anesthesia is a recognized technique for neonates and small children. The advent of the subarachnoid microcatheter technique potentially expands the use of spinal anesthesia. The authors studied the use of repeated neuroblock via spinal catheters in 10 children under 5 years, undergoing major abdominal surgery of 2 hours or longer. ⋯ The technique was a very effective method of providing adjunct operative anesthesia in infants and small children. Analgesia, muscle relaxation, and cardiovascular stability were present and no complications arose besides the apparent cerebrospinal fluid leak. The resultant risk of infection or possible duracutaneous fistula formation contraindicates the use of subarachnoid catheters of 28 gauge for postoperative analgesic use in young children.