Regional anesthesia
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Regional anesthesia · May 1996
Randomized Controlled Trial Clinical TrialComparison of intravenous nalbuphine infusion versus saline as an adjuvant for epidural morphine.
Radical (three-quadrant) hemorrhoidectomy is a major anorectal surgery that may necessitate aggressive pain management. This study was undertaken to determine whether intravenous nalbuphine infusion as an adjuvant to epidural morphine could offer not only a good quality of pain relief but also a lower incidence of side effects. ⋯ The results suggest that intravenous nalbuphine infusion as an adjuvant for epidural morphine reduces the incidence of side effects without decreasing the quality of pain relief.
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Regional anesthesia · May 1996
Randomized Controlled Trial Comparative Study Clinical TrialSpinal analgesia during labor with low-dose bupivacaine, sufentanil, and epinephrine. A comparison with epidural analgesia.
The purpose of this investigation was to evaluate the effectiveness and side effects of combined spinal-epidural (CSE) injection of a bupiv-acaine-sufentanil-epinephrine mixture during labor as compared with epidural analgesia alone. ⋯ The CSE mixture induced long-lasting analgesia, with fast onset and without motor block or hypotension. Pruritus and headache were the major drawbacks of this technique.
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Regional anesthesia · Mar 1996
Randomized Controlled Trial Clinical TrialSpinal anesthesia. Volume or concentration--what matters?
An investigation was made of the effects of volume and concentration of a constant dose of subarachnoid lidocaine on the extent and duration of sensory and motor anesthesia produced, as well as of the lidocaine concentration of the cerebrospinal fluid (CSF) as a function of time. ⋯ A constant 70-mg dose of subarachnoid lidocaine produced the same pinprick level of analgesia, degree of motor block, and duration of spinal anesthesia in spite of being injected over an extremely broad range of concentrations and volumes. Despite the fact that all patients received the same dose of lidocaine, the CSF concentrations at 5, 10, and 15 minutes were different and directly related to the concentration of the solution injected. at 20 minutes, the CSF concentrations were similar in all groups. These results indicate a relatively uniform distribution of lidocaine in the CSF for all solutions tested.
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Regional anesthesia · Mar 1996
Randomized Controlled Trial Clinical TrialAnalgesic effect of incisional morphine following inguinal herniotomy under spinal anesthesia.
Opioids have been shown to possess antinociceptive effects after peripheral administration in experimental and clinical studies. The results of clinical studies on intra-articularly administered morphine are, however, conflicting. The objective of this study was to examine a possible analgesic effect of incisionally administered morphine on postoperative pain in patients undergoing inguinal herniotomy. ⋯ A single 5-mg dose of morphine injected in the herniotomy wound did not affect pain scores or supplementary analgesic requirements, which argues against a role of peripheral opioid receptors in mediating analgesia.
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Regional anesthesia · Mar 1996
Randomized Controlled Trial Comparative Study Clinical TrialA comparison of meperidine and lidocaine for spinal anesthesia for postpartum tubal ligation.
This study compares the anesthetic potency, duration, and side effects of subarachnoid meperidine and lidocaine for postpartum tubal ligation. ⋯ Subarachnoid meperidine and lidocaine both provide adequate anesthesia for postpartum tubal ligation. Meperidine provided longer postoperative analgesia.