Casopís lékar̆ů c̆eských
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Casopís lékar̆ů c̆eských · Jan 2013
[Irreversible electroporation: local, non-thermal, ablation therapy of malignant tumours].
Irreversible electroporation (IRE) is a new method of local therapy of malign tumours based on bioelectric effect of electrical current. Short electric pulses with high voltage create nano size-pores in tumour cell membranes resulting in apoptosis of the exposed cells. The purpose of our study was to verify the IRE technique performed percutaneously under CT navigation and to assess effects of application of this method in early stages of primary and secondary hepatic, pancreatic, renal and pulmonary tumours. ⋯ IRE is a new, mini-invasive therapeutic method applicable to local treatment of malignant tumours in cases where surgical approach is technically unfeasible or excessively risky. On the basis of first experience in a small cohort of patients IRE performed under CT navigation appears to be an effective and safe ablation method with a large therapeutic potential. Its results will however need to be assessed within a longer time horizon and in a larger cohort of population.
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Hip fractures are ranked among the frequent injuries. These fractures have been often coupled with high energy trauma in children and in patients with normal bone structure, low energy trauma and osteoporotic fracture (fragility fracture) is typical in elder patients. Hip fractures are divided into five groups: femoral head fracture, femoral neck fracture, pertrochanteric, intertrochateric and subtrochanteric fracture. ⋯ Subtrochanteric fractures can be fixed also intramedullary (nails - PFN long, PFN A long) and extramedullary (plates - DCS dynamic condylar screw, proximal femoral LCP - locking compression plate). Open reduction with internal plate fixation is advantageous for pathological fractures, as biopsy sampling can be performed. Hip fracture rehabilitation is integral part of the treatment, including walking on crutches or with a walker with partial weight bearing for at least six weeks.
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Isolated calf vein thrombosis in the population of patients with deep vein thrombosis is found approximately in 10 to 25 % of cases. We present 3 cases of calf vein thrombosis which occurred due to unusual causes. Specific characteristics of this form of thromboembolic disease are discussed and compared to proximal deep vein thrombosis with emphasis to symptoms, risk of complications, prognosis and therapeutic approach.
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Casopís lékar̆ů c̆eských · Jan 2012
[Determination of needs of terminally ill patients in the hospice care].
The aim of palliative care is the solution of bio-psycho-social and spiritual problems of patients and achievement of the highest possible quality of life. This is related to a need of understanding the patient and his needs. The aim of our research was to determine bio-psychosocial-spiritual needs of patients in hospice care in conjunction with the quality of life and rate of their saturation. Further then to determine, whether the needs vary depending on length of stay in hospice, gender, age and religion. ⋯ During the stay in hospice patients' satisfaction with saturation of some needs and overall assessment of quality of life increased.
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The article describes the situation of the Czechoslovak exile, especially the exile of physicians to Sweden. Many of Czechoslovak physicians decided to emigrate due to their political attitudes. Majority of them left Czechoslovakia after the invasion of Warsaw Pact armies in 1968. ⋯ After one year of service in northern part of Sweden, where there was a lack of physicians, they could choose hospital, where they wanted to work. Czechoslovak physicians were very successful in the Swedish medical system and also well accepted in the Swedish society as other exulants from Czechoslovakia. Key words: Czechoslovak exile to Sweden, political asylum 1968-1968.