Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
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Zhonghua Wei Chang Wai Ke Za Zhi · Jan 2011
[Gene methylation in stool for the screening of colorectal cancer and pre-malignant lesions].
To evaluate association between DNA methylation of MAL, CDKN2A, and MGMT in stool and development of colorectal cancer, and to evaluate the screening value of these biomarkers in colorectal cancer and pre-malignant lesions. ⋯ DNA methylations levels of MAL, CDKN2A, and MGMT in stools are significantly higher in colorectal cancer and colon adenoma, which may serve as an noninvasive approach for the screening of colorectal cancer and pre-malignant lesions.
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Zhonghua Wei Chang Wai Ke Za Zhi · Jan 2011
Editorial["Damage control surgery" concept in gastrointestinal surgery].
In recent years, damage control is well established as a potentially life-saving procedure in a few selected critically injured patients. The "damage control" concept also has been shown to increase overall survival and is likely to modify the management of critically ill patients suffering from gastrointestinal disease. In these patients the "lethal triad" of hypothermia, acidosis, and coagulopathy acts as a vicious cycle that often can not be interrupted and marks the limit of the patient's ability to cope with the physiological consequences of traditional and extensive surgical procedures. ⋯ During the initial operation, the surgeon carries out only the absolute minimum necessary to improve patient's condition and to control bleeding, obstruction, and/or infection. The second phase consists of secondary resuscitation in the intensive care unit, characterized by maximization of hemodynamics, correction of coagulopathy, rewarming, and complete ventilatory support. During the third phase, definitive operation is performed.
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Zhonghua Wei Chang Wai Ke Za Zhi · Jul 2010
Randomized Controlled Trial[Effect of bowel preparation with probiotics on intestinal barrier after surgery for colorectal cancer].
To study the effect of bowel preparation with probiotics on intestinal barrier function after surgery for colorectal cancer. ⋯ One-day bowel preparation with probiotics can maintain the intestinal barrier function after surgery of colorectal cancer,which is suitable for elective colorectal surgery.
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Zhonghua Wei Chang Wai Ke Za Zhi · Mar 2010
[Expression and clinical significance of 14-3-3 sigma and heat shock protein 27 in colorectal cancer].
To investigate the expression of 14-3-3 sigma and heat shock protein 27 (HSP27) in colorectal carcinoma(CRC) tissue and its clinical significance. ⋯ The abnormal expression of 14-3-3 sigma and HSP27 is significantly associated with LNM in CRC.