Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
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Conf Proc IEEE Eng Med Biol Soc · Jan 2011
Biometric and mobile gait analysis for early diagnosis and therapy monitoring in Parkinson's disease.
Parkinson's disease (PD) is the most frequent neurodegenerative movement disorder. Early diagnosis and effective therapy monitoring is an important prerequisite to treat patients and reduce health care costs. Objective and non-invasive assessment strategies are an urgent need in order to achieve this goal. ⋯ The presented system is able to classify patients and controls (for early diagnosis) with a sensitivity of 88% and a specificity of 86%. In addition it is possible to distinguish mild from severe gait impairment (for therapy monitoring) with 100% sensitivity and 100% specificity. This system may be able to objectively classify PD gait patterns providing important and complementary information for patients, caregivers and therapists.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2011
Instrumentation to record evoked potentials for closed-loop control of deep brain stimulation.
Closed-loop deep brain stimulation (DBS) systems offer promise in relieving the clinical burden of stimulus parameter selection and improving treatment outcomes. In such a system, a feedback signal is used to adjust automatically stimulation parameters and optimize the efficacy of stimulation. We explored the feasibility of recording electrically evoked compound action potentials (ECAPs) during DBS for use as a feedback control signal. ⋯ Subsequently, the instrumentation was used to make in vivo recordings of ECAPs during thalamic DBS in cats, without contamination by the stimulus artifact. The signal characteristics were similar across three experiments, suggesting common neural activation patterns. The ECAP recordings enabled with this novel instrumentation may provide insight into the type and spatial extent of neural elements activated during DBS, and could serve as feedback control signals for closed-loop systems.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2011
Scalable patients tracking framework for mass casualty incidents.
We introduce a system that tracks patients in a Mass Casualty Incident (MCI) using active RFID triage tags and mobile anchor points (DM-tracks) carried by the paramedics. The system does not involve any fixed deployment of the localization devices while maintaining a low cost triage tag. The localization accuracy is comparable to GPS systems without incurring the cost of providing a GPS based device to every patient in the disaster scene.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2011
The frequency of saccades correlates to peak velocity in symmetrical disparity vergence.
A pure vergence stimulus requires the two eyes to turn equally inward or outward theoretically resulting in a pure symmetrical vergence response. However, saccades, a rapid conjugate eye movement, are frequently observed in vergence responses. This investigation sought to systematically quantify whether the occurrence of saccades within symmetrical vergence responses is correlated to vergence peak velocity. ⋯ The occurrence of saccades is negatively correlated to vergence peak velocity. When the velocity is slower, the number of saccades increases. This study suggests that the brain may initiate a saccade to facilitate a slow vergence movement, potentially to allow object recognition before binocular fusion.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2011
Estimation of baroreflex sensitivity during anesthesia induction with propofol.
This paper presents the analysis of the autonomic nervous system (ANS) control and cardiac baroreflex sensitivity in patients undergoing general anesthesia for major surgery, with the goal of evaluating the effects of anesthesia bolus induction with propofol on autonomic control of heart rate (HR) and arterial blood pressure (ABP). The increase in baroreflex gain in the LF band observed through two different methods hints at the fact that the baroreflex may increase heart period (HP) following a transient ABP decrease, but its response displays a larger amplitude, to compensate for the blunting of the sympathetic action on heart rate and vascular resistance.