Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
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Depth of anesthesia can be indirectly measured by Bispectral Index (BIS), therefore it is possible to administer propofol in a closed loop to maintain the optimal level of anesthesia while minimizing the dose to improve the postanesthesia recovery. High-Order Sliding-Mode control can be used to individualize drug dosing. In this study, the controller is tested with four in silico patients.
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An ultra-low-cost pulse oximeter is presented that interfaces a conventional clinical finger sensor with a mobile phone through the headset jack audio interface. All signal processing is performed using the audio subsystem of the phone. In a preliminary volunteer study in a hypoxia chamber, we compared the oxygen saturation obtained with the audio pulse oximeter against a commercially available (and FDA approved) reference pulse oximeter (Nonin Xpod). Good agreement was found between the outputs of the two devices.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2013
An EEG diagnosis system for quasi brain death based on complexity and energy analyses.
Electroencephalogram (EEG) is often used in confirmatory test for brain death determination in clinical practice. Because the EEG measuring and monitoring is relatively safe and reliable for deep comatose patients, it is believed to be valuable for reducing the risk of diagnosis or prevent mistaken diagnosis of brain death. In this paper, we present EEG complexity analysis and EEG energy analyses for the EEG acquisition of 35 adult patients. ⋯ In EEG energy analysis, we firstly accumulate the EEG energy from the extracted components that are related to the brain activities. Then, we evaluate the energy differences between deep comatose patients and brain death. The empirical results reported in this paper suggest some promising directions and valuable clues for clinical practice.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2013
Automatic control system of brain temperature by air-surface cooling for therapeutic hypothermia.
An automatic control system of brain temperature by air-surface cooling was developed for therapeutic hypothermia, which is increasingly recommended for hypoxic-ischemic encephalopathy after cardiac arrest and neonatal asphyxia in several guidelines pertinent to resuscitation. Currently, water-surface cooling is the most widespread cooling method in therapeutic hypothermia. However, it requires large electric power for precise control and also needs water-cooling blankets which have potential for compression of patients by its own weight and for water leakage in ICU. ⋯ The control performance of the suggested system was verified by the examination using the mannequin in substitution for an adult patient. In the result, the control error of the head temperature of the mannequin was 0.12 °C on average in spite of the lack of the production capacity of warm air after the re-warming period. Thus, this system serves as a model for the clinically applied system.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2013
A cepstral analysis based method for quantifying the depth of anesthesia from human EEG.
In this paper, a cepstral analysis based approach to measuring the depth of anesthesia (DoA) is presented. Cepstral analysis is a signal processing technique widely used especially for speech recognition in order to extract speech information regardless of vocal cord characteristics. The resulting index for the DoA is called index based on cepstral analysis (ICep). ⋯ All analyses are based on a single-channel electroencephalogram (EEG) of 10 human subjects. To validate the proposed technique, ICep is compared with bispectral index (BIS), which is the most commonly used method to estimate the level of consciousness via EEG during general anesthesia. The results show that ICep has high correlation with BIS, and is outstanding in terms of the Fisher criterion and offers faster tracking than BIS in the transition from consciousness to unconsciousness.