Revista médica de Chile
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Nonmotor symptoms of Parkinson disease significantly hamper the quality of life of patients and have prognostic significance. ⋯ Nonmotor symptoms must be actively sought and managed in patients with Parkinson disease.
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Revista médica de Chile · Aug 2020
[A revision about health care management in public services and municipalities in Chile].
An appropriate conceptualization process, consisting of an in-depth reflection about the role of organisms responsible for primary health care, which in Chile are the municipalities, should be carried out. Such exercise should enable the development of an analytical method aiming to understand management problems and bottlenecks in a determinate territory or region. Thus, changes to improve resource use effectiveness, with an impact in population health, could be proposed.
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Revista médica de Chile · Aug 2020
Review[Risk of infections associated with the use of biological medications; a review].
Biological medications are effective for the treatment of cancer and inflammatory diseases. The aim of this review is to summarize the available evidence in systematic reviews or meta-analyses about the risk of infection in patients with cancer, arthritis, psoriasis and inflammatory bowel disease who use biological medications. We included systematic reviews or meta-analyses of controlled clinical trials and case/control studies that analyze infections during and after treatment with FDA-approved biological medications for the treatment of cancer, arthritis, inflammatory bowel disease and psoriasis, both in adults and children. ⋯ In inflammatory bowel disease there is a risk for opportunistic infections. In conclusion, in patients with cancer and inflammatory diseases use biological medications entails a risk of infection. The evidence is different depending on the underlying disease of each patient.