La Revue du praticien
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Pulmonary arterial hypertension (PAH) is a rare condition characterised by elevated pulmonary arterial resistance leading to right heart failure. PAH can be sporadic (idiopathic PAH, or primary pulmonary hypertension), familial (caused by germline BMPR2 mutations, a type II member of the TGFbeta receptor superfamily), or related to other conditions including connective tissue disease, congenital heart disease, human immunodeficiency virus infection, portal hypertension, appetite suppressant exposure... Idiopathic PAH has a prevalence of 2 per million per year in France. ⋯ Recent advances in the management of PAH including continuous intravenous prostacyclin infusion and endothelin receptor antagonists have improved markedly the patients' prognosis. Novel treatments such as inhaled iloprost and type 5 phosphodiesterase inhibitors have to be further evaluated in this setting. Lung transplantation is the last option for patients deteriorating despite medical treatment.
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Neurological complications of cancer are common, and some of them are true emergency. Rapid diagnosis and treatment can preserve neurologic functions and sometimes save a life. Raised intracranial pressure, epilepsy, spinal cord compression, cerebral vascular complication and infectious meningitis are the most common neurologic emergencies in cancer patient.
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La Revue du praticien · Nov 2003
Review Comparative Study[Cough in the child and in the adult (with treatment)].
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The medical history and the physical examination are the most important parts of the diagnosis of groin adults' hernias. The examination will be done the patient initially stand up. The doctor examines the external inguinal ring, the internal inguinal ring and the floor of the inguinal canal. ⋯ In these cases, ultrasonography could be a good opportunity, like in cases of unexplained groin tumours. TDM is a good exam, only to explore the content and the parietal defect of large, old, fixed hernias. In fact, it is important to remember that groin hernia could be a symptom of colon, rectum, or prostatic diseases, secondary to intraabdominal pressure.