La Revue du praticien
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La Revue du praticien · Jan 2013
Review[Acute mountain sickness and high altitude cerebral and pulmonary edema].
Altitude hypoxia is responsible for acute mountain sickness. It can worsen and generate a high altitude cerebral edema, which can be fatal. After reminding the reader clinical and epidemiological facts, this review aims to present new insights of the physiopathological continuity between these two illnesses and the current preventive and treatment tools. Have new medications, as sumatriptans, kept their promises? Have recent studies provide evidence of empirical use of old drugs as aspirin or ibuprofen? What are acetazolamide and dexamethasone places? This wide range of medication doesn't replace non-pharmacological tools.
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La Revue du praticien · Dec 2012
Review[Drug reaction with eosinophilia and systemic symptoms (DRESS)].
DRESS (drug reaction with Eosinophilia and systemic symptoms) is a syndrome classically considered as a severe cutaneous drug adverse reaction. But visceral manifestations (renal, liver, lung, heart...) may be at the forefront. It presents clinically as an exanthema evolving to erythroderma with facial edema, associated with lymphadenopathy, high fever, visceral involvement (hepatitis, renal failure, pneumonitis, or hemophagocytic syndrome), eosinophilia preceded by lymphopenia and/or atypical lymphocytes. ⋯ It is induced by some drugs (allopurinol, anticonvulsants, sulfasalazine, minocycine...). Its early diagnosis is necessary for a rapid discontinuation of the culprit drug. Its management includes a long-term followup, and according to the severity either topical steroids, systemic steroids, intravenous gammaglobulins, or antiviral.
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La Revue du praticien · Jun 2012
Review Historical Article[Analgesic and anesthetic plants in Roman antiquity].