Zhonghua fu chan ke za zhi
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Zhonghua Fu Chan Ke Za Zhi · Aug 2014
[Correlation between TCF7L2 gene polymorphism and genetic susceptibility in women with gestational diabetes mellitus].
To investigate the relationship between single nucleotide polymorphism (SNP) of transcription factor 7-like 2 (TCF7L2) at locus rs7903146, rs290487, rsl1196205, rs12255372 and genetic susceptibility in women with gestational diabetes mellitus (GDM). ⋯ The polymorphism of locus rs7903146 in TCF7L2 gene may be associated with genetic susceptibility in women with GDM. TT genotype is likely to be risk factor in the pathogenesis of GDM.
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Zhonghua Fu Chan Ke Za Zhi · Jul 2014
[Analysis of high risk factors for patient death and its clinical characteristics on pregnancy associated with pulmonary arterial hypertension].
Study of pulmonary hypertension (PAH) during pregnancy has characteristics of the high risk factors for patient death and its clinical characteristics. ⋯ (1) PAH in patients need for consultation prior to conception, pregnancy must conduct regular prenatal examination, symptoms occur during pregnancy, the cardiac function was significantly decreased, and no improvement of drug treatment should be early terminated the pregnancy. (2) Compared with the pregnant women with CHD- PAH, faster progress and poor prognosis in patients with IPAH disease. (3)The patients during cesarean operation or intrapartumare easy to cause PAH crisis and heart failure or multiple organ failure. Taking active measures to maintain stability of hemodynamics is the key to prevent the occurrence of death of pregnant women with PAH.
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Zhonghua Fu Chan Ke Za Zhi · Jun 2014
[Severe idiopathic pulmonary arterial hypertension in pregnancy: a review of 10 cases].
To study the impact of severe idiopathic pulmonary arterial hypertension (IPAH) on pregnancy outcome and to investigate the effect of multidisciplinary approach during pregnancy on the pregnancy outcome in pregnant woman with severe IPAH. ⋯ Because of maternal mortality in patients with severe IPAH remains prohibitively high, patients should continue to be counseled to avoid pregnancy.Women with severe IPAH who become pregnancy should be followed by multidisciplinary approach, and cesarean deliveries during continuous epidural anesthesia are a relatively safe way for pregnancy termination in patients with severe IPAH.
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Zhonghua Fu Chan Ke Za Zhi · Jun 2014
Randomized Controlled Trial[Clinical study on sildenafil in treatment of pregnant women with pulmonary arterial hypertension].
To explored the effect of sildenafil in treatment of pregnant women with pulmonary arterial hypertension. ⋯ Sildenafil treatment can significantly improve the clinical symptoms, cardiac function and hemodynamic parameters.It also could significantly improve pregnancy outcomes, reduce premature delivery, the incidence of low birth weight children, and cesarean section rate.
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Zhonghua Fu Chan Ke Za Zhi · May 2014
[Evaluation of postoperative bladder function and prognosis after modified nerve sparing radical hysterectomy].
To compare the nerve plane sparing radical hysterectomy (NPSRH) with conventional radical hysterectomy (CRH) in terms of postoperative bladder function and prognosis. ⋯ NPSRH contributes to bladder function recovery without compromising survival.