Langenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress
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Langenbecks Arch Chir Suppl Kongressbd · Jan 1998
[Tumor necrosis factor-alpha (TNF-alpha) gene polymorphism in surgical intensive care patients with SIRS].
Biallelic polymorphism in the promotor region of the TNF-alpha gene have been associated with variation in TNF-alpha production. We determined the TNFA polymorphism (position--308) and related these data to plasma cytokine levels of TNF alpha, IL6, IL6R and IL8 in patients with SIRS and sepsis. Although there seems to be a different cytokine secretion pattern for both allelic groups (TNFA1 and TNFA2), a clear risk group could not be determined. It still remains unclear whether there is a genetic factor that influences the development of sepsis and multi organ failure.
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Langenbecks Arch Chir Suppl Kongressbd · Jan 1998
[Information exchange via internet--possibilities, limits, future].
Today, the exchange of information in the Internet is dominated by the WWW and e-mail. Discussion groups like mailing lists and newsgroups also permit communication in groups. Information retrieval becomes a crucial challenge in using the Internet. ⋯ Future developments will not only improve the existing services, but also lead to fundamental changes in the transfer technologies: Safer data transfer is to be ensured by new encrypting software together with the planned transfer protocol IPv6. Introducing the new transfer mode ATM will lead to better and resource saving transmission. Computer, telephone and TV networks will grow together, resulting in convergence of media.
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Langenbecks Arch Chir Suppl Kongressbd · Jan 1998
Comparative Study[Effect of pneumoperitoneum with carbon dioxide and helium on hemodynamic parameters after compensated acute hemorrhage].
If animals have been properly resuscitated after moderate bleeding and hypovolemia has been corrected with colloidal solution, pneumoperitoneum with 12 mmHg does not appear to be harmful in a porcine model. Helium showed no clear advantage as insufflating gas over carbon dioxide.
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Langenbecks Arch Chir Suppl Kongressbd · Jan 1998
Comparative Study[Quality of life after inguinal hernia operation--results of a prospective study (Shouldice, Lichtenstein, TAPP)].
Data concerning quality of life and rehabilitation after inguinal hernia repair are still poor. A prospective survey on 269 patients was conducted following standardized Shouldice, Lichtenstein and TAPP hernioplasty by means of questionnaire. General health perception, pain scores and physical activity were significantly improved by all of the mentioned techniques. Laparoscopic repair was beneficial in indirect, recurrent and bilateral hernia and small defects of the transverse fascia.
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Langenbecks Arch Chir Suppl Kongressbd · Jan 1998
Case Reports[Medical principles of thromboembolism prevention].
Since thromboembolic complications have been described to be one of the most frequent complications following surgery, a correct indication for prophylaxis is of great clinical importance. This requires comprehensive knowledge about the general thrombosis risk of various patient populations, experience in the assessment of the individual thrombosis risk, understanding of the mode of action of various prophylaxis modalities, and critical benefit/risk assessment when pharmacological agents are used. Patients with a moderate or high risk require medical prophylaxis with either unfractionated heparin, low molecular weight heparins, or oral anticoagulants unless there is too high a risk of bleeding. Mechanical methods such as physical exercise and early mobilisation of the patient remain the basic measurements which can be supplemented by graduated pressure stockings.