Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
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Beijing Da Xue Xue Bao · Oct 2015
[Protective effect of phloroglucinol on renal ischemia and reperfusion injury].
To investigate the effect and mechanisms of Phloroglucinol (PG) on renal ischemia and reperfusion injury (IRI). ⋯ PG protects murine kidney I/R injury by suppressing oxidative stress, inflammation, and cell apoptosis.
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Beijing Da Xue Xue Bao · Oct 2015
Case Reports[Rocuronium anesthesia induced anaphylactic shock: a case report].
Anaphylaxis is an acute and fatal systemic allergic reaction to an allergen, and it could be an unpredictable and life-threatening cause during anesthesia. The main purpose of this paper is to report a case of anaphylactic shock during the anesthesia induction and to review the prophylaxis and treatment of anaphylactic reactions and anaphylactoid reactions during the anesthesia period. A 63-year-old man, with a mass on his adrenal, was scheduled to a laparoscopic adrenal tumor excision. ⋯ Anaphylactic reactions in the perioperative period are often serious and potentially life-threatening conditions, involving multiple organ systems in which the clinical manifestations are the consequence of the release of preformed mediators from mast cells and basophils. Before anesthesia, we should acquire the allergic history. During the anesthesia period, the vital sign and the skin should be observed carefully.
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Beijing Da Xue Xue Bao · Aug 2015
[Detection of cytochrome P450 3A4 gene polymorphism guides for labor analgesia with sufentanil medication].
To investigate the relationship between single nucleotide polymorphisms (SNPs) of cytochrome P450 (CYP450) 3A4 rs2242480 and inter-individual differences of sufentanil consumption in accouchement sans douleur. ⋯ The parturient women carrying CT heterozygotes and TT homozygotes of CYP3A4 rs2242480 required less sufentanil in accouchement sans douleur.
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Beijing Da Xue Xue Bao · Aug 2015
[Effects of sevoflurane on brain neuroapoptosis and ability of long-term learning and memory in newborn rats].
To investigate the changes of neuroapoptosis in brain and learning ability after neonatal mice are exposed to inhaled sevoflurane. ⋯ Exposure to the concentration of 2% sevoflurane causes brain cell apoptosis of newborn rats. The memory ability to pessimal stimulation is decreased as the anesthesia mice were 5-week-old, such changes recede along with the growth of the rats. Exposure to the concentration of 2% sevoflurane does not affect the spatial reference memory of newborn rats during their growth.
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Beijing Da Xue Xue Bao · Aug 2015
Randomized Controlled Trial[Influence of dexamethasone on the incidence of postoperative nausea and vomiting in breast cancer patients with neoadjuvant chemotherapy].
To evaluate the influence of dexamethasone on the incidence of postoperative nausea and vomiting (PONV) in patients undergoing modified radical mastectomy with neoadjuvant chemotherapy. ⋯ Dexamethasone prevents PONV effectively in patients undergoing modified radical mastectomy with neoadjuvant chemotherapy, and TIVA cannot decrease the incidence of PONV in the 24-hour postoperative period in those patients.