Current review of pain
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Current review of pain · Jan 2000
ReviewNeuromodulation: spinal cord and peripheral nerve stimulation.
Spinal cord and peripheral nerve stimulation for relief of chronic intractable pain have been used since the mid-1960s. Multiple mechanisms of action have been theorized without a clear-cut winner. ⋯ Efficacy studies consistently show an overall 50% improvement in long-term pain control in patients who have failed conservative or other invasive modalities. With improvements in today's technology, one hopes that better analgesia will be attainable.
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Current review of pain · Jan 2000
ReviewPain complaints in patients with fibromyalgia versus chronic fatigue syndrome.
Individuals with fibromyalgia (FM) and/or chronic fatigue syndrome (CFS) report arthralgias and myalgias. However, only persons with FM alone exhibit abnormal pain responses to mild levels of stimulation, or allodynia. We identify the abnormalities in the neuroendocrine axes that are common to FM and CFS as well as the abnormalities in central neuropeptide levels and functional brain activity that differentiate these disorders. These two sets of factors, respectively, may account for the similarities and differences in the pain experiences of persons with FM and CFS.
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Over the years, a number of treatments for persistent low back pain following spine surgery, the failed back surgery syndrome (FBSS), have been developed. The complexity of the clinical problem, the multidimensional nature of chronic pain, and general lack of rigorous study design, however, have obscured outcome assessment and hampered efforts to optimize patient selection criteria. Recent work has focused on refinement of existing therapies for FBSS and identification of factors that influence outcome and improve patient selection criteria. In combination with more rigorous study methodology, these efforts have led to improved understanding of the clinical response to a number of pharmacologic, surgical, and neuromodulation therapies for FBSS.
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Current review of pain · Jan 2000
ReviewReflex sympathetic dystrophy: a sympathetically mediated pain syndrome or not?
Because of the controversy concerning the manner in which the sympathetic nervous system is involved in reflex sympathetic dystrophy (RSD), its name was changed to one having no mechanistic connotations. This article reviews the relevant literature in support of not only the taxonomical changes to complex regional pain syndrome (CRPS) but also provides evidence of sympathetic dysfunction demonstrated in animal models of neuropathic pain.
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Uncommon stimulation refers to the use of peripheral nerve and spinal cord stimulation for nontraditional applications. There has been much interest recently with subcutaneous suboccipital stimulation for occipital neuralgia, sacral stimulation for pelvic pain, trigeminal stimulation for trigeminal neuralgia, and spinal cord stimulation for angina and peripheral ischemia. The indications and techniques used for accomplishing each method are discussed.