Mayo Clinic proceedings
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Mayo Clinic proceedings · Oct 2013
Review Meta AnalysisEndovascular therapy for acute ischemic stroke: a systematic review and meta-analysis.
To consolidate the evidence from randomized trials for the use of endovascular therapy (ET) in patients with acute ischemic stroke. ⋯ Overall, ET is not superior to IV thrombolysis for acute ischemic strokes (level B recommendation). However, ET showed promise and improved outcomes in patients with severe strokes, but the evidence is limited due to sample size. There is a need for further trials evaluating the role of ET in this high-risk group.
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Mayo Clinic proceedings · Oct 2013
Comparative StudyImproving affordability through innovation in the surgical treatment of mitral valve disease.
To determine whether technically innovative cardiac surgical platforms (ie, robotics) deployed in conjunction with surgical process improvement (systems innovation) influence total hospital costs to address the concern that expanding adoption might increase health care expenses. ⋯ Following the introduction of systems innovation, the total hospital cost associated with robotic mitral valve repair has become similar to that for a conventional open approach, while facilitating quicker patient recovery and diminished utilization of in-hospital resources. These data suggest that innovations in techniques (robotics) along with care systems (process improvement) can be cost-neutral, thereby improving the affordability of new technologies capable of improving early patient outcomes.
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Mayo Clinic proceedings · Oct 2013
Proton Pump Inhibitors and the Risk for Hospital-Acquired Clostridium difficile Infection.
To examine the relationship between proton pump inhibitor (PPI) usage and nosocomial Clostridium difficile infection (CDI) and determine the duration of therapy at which CDI risk increases. ⋯ The duration of PPI therapy is significantly associated with CDI. Clinicians should strongly consider restricting PPI use given the short exposure time associated with this increased risk.
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Mayo Clinic proceedings · Oct 2013
Association of coffee consumption with all-cause and cardiovascular disease mortality.
To evaluate the association between coffee consumption and mortality from all causes and from cardiovascular disease. ⋯ In this large cohort, a positive association between coffee consumption and all-cause mortality was observed in men and in men and women younger than 55 years. On the basis of these findings, it seems appropriate to suggest that younger people avoid heavy coffee consumption (ie, averaging >4 cups per day). However, this finding should be assessed in future studies of other populations.