Mayo Clinic proceedings
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Mayo Clinic proceedings · Sep 2019
Multicenter StudyModel for End-Stage Liver Disease Score Predicts Development of First Episode of Spontaneous Bacterial Peritonitis in Patients With Cirrhosis.
To examine whether baseline model for end-stage liver disease (MELD) score in patients with cirrhosis and ascites predicts the future development of first spontaneous bacterial peritonitis (SBP) episode. ⋯ Baseline MELD score predicts first SBP episode in patients with cirrhosis and ascites.
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Mayo Clinic proceedings · Sep 2019
Clinical Applications and Utility of a Precision Medicine Approach for Patients With Unexplained Cytopenias.
To demonstrate experience and feasibility of a precision medicine approach for patients with unexplained cytopenias, defined as low blood counts in one or more cell lineages, persistent for 6 months or longer, in the absence of known nutritional, autoimmune, infectious, toxic, and neoplastic (secondary) causes. ⋯ We show clinical utility of a real-world algorithmic precision medicine approach for unexplained cytopenias.
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Mayo Clinic proceedings · Sep 2019
Review Case Reports60-Year-Old Man With Syncope, Abdominal Pain, and Hematochezia.
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Mayo Clinic proceedings · Sep 2019
Survival and Progression in Synucleinopathy Phenotypes With Parkinsonism: A Population-Based Study.
To compare survival by the presenting parkinsonism symptoms at diagnosis among patients with incident clinically diagnosed synucleinopathies. ⋯ Patients with tremor as a presenting symptom have longer survival. In contrast, the presence of bradykinesia/rigidity as a presenting symptom correlates with reduced survival across all types of synucleinopathies.
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Mayo Clinic proceedings · Sep 2019
High Prevalence of Celiac Disease Among Screened First-Degree Relatives.
To investigate the prevalence of first-degree relatives (FDRs) with celiac disease detected at screening and diagnostic significance of anti-tissue transglutaminase (anti-TTG). ⋯ In a retrospective cohort study of patients diagnosed with celiac disease, we found a high prevalence of celiac disease among screened FDRs. High anti-TTG titers associated with villous atrophy on small bowel biopsies, irrespective of symptoms.