Nan fang yi ke da xue xue bao = Journal of Southern Medical University
-
Nan Fang Yi Ke Da Xue Xue Bao · Apr 2020
Review[Application of laboratory diagnostic technologies for SARS-CoV-2: current progress and prospect].
Since the outbreak of COVID-19 pandemic, the detection capability has been improving and the detection techniques have been evolving with innovations. qRT- PCR and mNGS, which represent the current mainstay diagnostic technologies, play key roles in disease diagnosis and monitoring of virus variation. The detection technologies based on serum and plasma IgM and IgG antibodies are important for auxiliary diagnosis. ⋯ These techniques all have great potential for future development and application for pathogen detection. In this review the authors summarize the basic rationales, technical characteristics and the current application of the SARS-CoV-2 detection techniques.
-
Nan Fang Yi Ke Da Xue Xue Bao · Feb 2020
Review[Artificial intelligence empowers laboratory medicine in Industry 4.0].
Since 2017, China, the United States, and the European Union have successively issued national-level artificial intelligence (AI) strategic development plans, and the human history is about to witness the 4th industrial revolution with the theme of "intelligence". In the field of medical testing, the explosive growth of AI theories and technologies also provide a new direction for the development of medical testing theory, methods and applications. ⋯ The major applications include specimen collection robots, sample dilution robots and sample transfer robots involved in the processing of test specimens; test item mining such as tumor markers and pharmacogenomics; cytomorphology, laboratory medicine data processing, auxiliary diagnostic models, and internet-based medical tests. With the advent of the era of Industry 4.0, AI technology will promote the development of medical testing from automation to a highly intelligent stage.
-
Nan Fang Yi Ke Da Xue Xue Bao · Sep 2019
Review[Research progress of the role of postoperative pain in the development of postoperative cognitive dysfunction in geriatric patients].
Previous studies have shown that postoperative cognitive dysfunction (POCD) is related to multiple factors including age, postoperative trauma, inflammation, postoperative pain, and anesthesia, among which postoperative pain is thought to play an important role in the development of POCD. This review summarizes the recent findings in the study of the role of postoperative pain in the pathogenesis of POCD in light of nerve injuries, neural remodeling and stress, and the progress in the prevention and treatment of POCD in elderly patients. It is of vital important to assess the postoperative pain and formulate adequate analgesic regimens for effective prevention and management of POCD to protect the brain functions of elderly patients.
-
Nan Fang Yi Ke Da Xue Xue Bao · Apr 2016
Review[Research progress of depression and the application of esketamine].
The pathogenesis and etiology of still remain unknown. Current evidence suggests that the occurrence of depression may be related to a reduced secretion of neurotransmitters, neuronal apoptosis, inflammation, intestinal flora and other factors. ⋯ Herein the authors review the progress in the study of the pathogenesis and drug therapies of depression, the efficacy of esketamine treatment and the underlying mechanism, and the prospect of esketamine treatment. Currently the mechanism of the antidepressant effect of esketamine remains indeterminate and its clinical application is limited, but its effect in rapidly alleviating the symptoms of depression suggests its bright prospect for clinical applications.
-
Nan Fang Yi Ke Da Xue Xue Bao · Nov 2015
Review[Application of precision medicine in the field of surgery].
Precision medicine, based on personalized medicine, is to provide personalized and precise treatment. The emergence of 3D printing technique as well as genome sequencing provides an effective way to realize precise and personalized treatment. ⋯ With the development of tissue engineering, new material technology and genome sequencing and the improvement in related polices and regulations, precision medicine will step on a higher level in the field of surgery. This review introduces the application of precision medicine in the field of surgery.