Nan fang yi ke da xue xue bao = Journal of Southern Medical University
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Nan Fang Yi Ke Da Xue Xue Bao · Feb 2013
[Human µ-opioid receptor A118G polymorphism affects epidural patient-controlled analgesia with fentanyl].
To investigate whether A118G single nucleotide polymorphisms of the µ-opioid receptor (OPRM1) affects epidural patient-controlled analgesia with fentanyl after caesarean section. ⋯ A118G single nucleotide polymorphism affects pain relief and total fentanyl dose administered in epidural patient-controlled analgesia after caesarean section. G118 homozygotes have a poorer response to fentanyl than A118 homozygotes or heterozygotes.
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Nan Fang Yi Ke Da Xue Xue Bao · Dec 2012
[Construction of let-7d expression vector and its inhibitory effect on HMGA2 and ras expression in human ovarian cancer cells in vitro].
To elucidate the role of let-7d in regulating the biological behavior of ovarian cancer cells and their expressions of HMGA2 and ras proteins. ⋯ Let-7d plays an important role in altering the malignant cell phenotype of ovarian cancer IGROV1 cells by regulating the expression of HMGA2.
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Nan Fang Yi Ke Da Xue Xue Bao · Nov 2012
Meta Analysis[Effect of propofol and inhalation anesthesia on postoperative cognitive dysfunction in the elderly: a meta-analysis].
To compare the effects of propofol and inhalation anesthesia on the incidence of early postoperative cognitive dysfunction (POCD) in elderly patients undergoing noncardiac surgeries. ⋯ Compared with inhalation anesthesia, propofol anesthesia is associated with a lower incidence of early POCD in elderly patients, but this conclusion needs to be further verified by more well-designed large-scale RCTs.
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Nan Fang Yi Ke Da Xue Xue Bao · Oct 2012
Randomized Controlled Trial[Effect of ulinastatin for hepatoprotection following extracorporeal membrane oxygenation].
To explore the effect of ulinastatin in hepatoprotection following extracorporeal membrane oxygenation (ECMO). ⋯ ECMO can significantly improve the liver function. The liver function damage reaches the peak level after a 12-h ECMO treatment, and ulinastatin can protect the liver function in patients undergoing ECMO.
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Nan Fang Yi Ke Da Xue Xue Bao · Sep 2012
[Effects of abdominal compartment syndrome on circulation and respiratory function in rabbits].
To establish a rabbit model of abdominal compartment syndrome (ACS) and evaluate the impact of ACS on cardiovascular and respiratory functions and blood electrolyte levels in rabbits. ⋯ IAB plus IAH may cause damage to the cardiovascular and respiratory functions and lead to ACS in rabbits.