Journal of cardiothoracic anesthesia
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J Cardiothorac Anesth · Jun 1988
Clinical TrialEffect of hypothermia on median nerve somatosensory evoked potentials.
Median nerve somatosensory evoked potentials (SEP) were monitored in ten patients undergoing cardiac surgery with hypothermic cardiopulmonary bypass (CPB). Anesthesia was induced and maintained with sufentanil, oxygen, and pancuronium. Esophageal, nasopharyngeal, rectal, and blood temperatures were continuously monitored. ⋯ There was a strong negative correlation between SEP latencies and temperature (except rectal) (r = -.91, P < .001). for cortical latency and esophageal temperature. A decrease in esophageal temperature of 1 degrees C resulted in an increase in SEP latency of 1 ms. There was also a weak positive correlation between evoked potential amplitude and temperature (r = .19) for cortical amplitude and esophageal temperature.
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J Cardiothorac Anesth · Jun 1988
Randomized Controlled Trial Comparative StudyComparative hemodynamic effects of propofol and thiamylal sodium during anesthetic induction for myocardial revascularization.
The safety and efficacy of propofol, a new intravenous anesthetic agent, have been demonstrated in healthy patients. Twenty-one patients, ASA III-IV, undergoing elective myocardial revascularization, were randomly chosen to receive either propofol, 2.5 mg/kg, or thiamylal, 4 mg/kg. for the induction of anesthesia. Hemodynamics were recorded at one and three minutes after drug administration during spontaneous respiration. ⋯ Both groups experienced significant increases in HR following intubation, but no evidence of myocardial ischemia was seen in either group. All other parameters returned toward control values. Propofol appeared to be safe and effective for the induction of anesthesia in this group of patients, although its hemodynamic effects were greater than those of thiamylal.
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J Cardiothorac Anesth · Jun 1988
Randomized Controlled Trial Comparative StudyLocal anesthesia for radial artery cannulation: a comparison of a lidocaine-prilocaine emulsion and lidocaine infiltration.
A topical anesthetic emulsion consisting of a mixture of lidocaine and prilocaine (EMLA) was used in an attempt to reduce the pain associated with radial artery cannulation. Three groups were compared: (1) EMLA applied at least 90 minutes prior to cannulation (EMLA 90); (2) EMLA applied 60 minutes prior to cannulation (EMLA 60); and (3) lidocaine 2% infiltration performed immediately prior to the procedure (infiltration). ⋯ There was no statistically significant difference in pain scores between the EMLA 60 and infiltration groups. Local side-effects of EMLA were negligible.