Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo
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Monaldi Arch Chest Dis · Jun 1994
Randomized Controlled Trial Clinical TrialVolume-controlled ventilation and pressure-controlled inverse ratio ventilation: a comparison of their effects in ARDS patients.
Volume-controlled ventilation with positive end-expiratory pressure (PEEP) (CPPV) is the conventional ventilatory approach in adult respiratory distress syndrome (ARDS) patients, but some reports suggest that pressure-controlled ventilation with an inverse inspiratory to expiratory ratio (PCIRV) may improve gas exchange in these patients. We analysed the acute effects on gas exchange, lung mechanics and haemodynamics induced by CPPV and PCIRV in ARDS patients. CPPV and PCIRV were applied randomly in ARDS patients. ⋯ Oxygen transport and total respiratory system compliance remained unchanged in both modes. Mean Paw was slightly lower during CPPV (17 +/- 1 cmH2O) than during PCIRV (19 +/- 1 cmH2O). PCIRV does not appear to have clinical advantages over CPPV in terms of gas exchange, haemodynamics, or static lung mechanics when using the same total PEEP and minute ventilation.