Gigiena i sanitariia
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Gigiena i sanitariia · Nov 2007
[Buccal epithelial micronuclear test in the comprehensive assessment of children's ecological well-being in Moscow].
In the buccal epithelial micronuclear test, only the higher frequency of cells with any nuclear degenerative changes is considered to be attributable to the adverse influence of environmental factors. Comprehensive examination of 223 children of 5-7 years of age, going to kindergartens and schools has indicated that the frequency of cells with nuclear chromatin condensation and incomplete nuclear lysis decreased when ambient air contamination was increased in the territories of children's establishments and when the child's throat was contaminated with Staphylococcus aureus or the pharyngeal resident microflora inhibited. ⋯ It is suggested that nuclear chromatin condensation and nuclear lysis (rather than other signs of cell degeneration and death) reflect natural cell aging. A moderate toxic effect causes epitheliocytic physiological development retardation and a more intensive effect accelerates aging of cells and induces their death.
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Gigiena i sanitariia · Sep 2007
Review[Topical problems of the comprehensive hygienic characterization of urban environmental factors and their influence on the population's health].
The authors consider the topical problems of the influence of urban environmental factors (the quality of drinking water, the pollution of the ambient and dwelling airs and soil) on the health of residents in the urbanized areas. They show it necessary to apply a comprehensive approach to studying and analyzing the influence of a large number of interrelated factors on the population's health and its vulnerable subgroups, by employing the current sensitive biomedical studies, as well as to develop and introduce noninvasive techniques for the early diagnosis of environment-induced diseases.