Yonsei medical journal
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Yonsei medical journal · Nov 2011
Co-immunization of plasmid DNA encoding IL-12 and IL-18 with Bacillus Calmette-Guérin vaccine against progressive tuberculosis.
Bacillus Calmette-Guérin (BCG) vaccine has widely been used to immunize against tuberculosis, but its protective efficacy is variable in adult pulmonary tuberculosis, while it is not efficiently protective against progressive infection of virulent Mycobacterium tuberculosis strains. In this study, the protective effects of plasmid DNA vaccine constructs encoding IL-12 or IL-18 with the BCG vaccine were evaluated against progressive infection of M. tuberculosis, using mouse aerosol challenge model. ⋯ Co-immunization of IL-12 DNA vaccine with the BCG vaccine induced more protective immunity and was more effective for protection against progressive infection of M. tuberculosis.
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Yonsei medical journal · Nov 2011
The effects of heat and massage application on autonomic nervous system.
The objective of this study is to evaluate the effects of heat and massage application on autonomic nervous system. ⋯ The results of this study suggest that heat and massage applications provide relaxation to the autonomic nervous system without serious adverse events.
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Yonsei medical journal · Nov 2011
Analgesic mechanism of electroacupuncture in an arthritic pain model of rats: a neurotransmitter study.
We investigated what kinds of neurotransmitters are related with electroacupuncture (EA) analgesia in an arthritic pain model of rats. ⋯ The analgesic effects of EA are related to opioid, adrenergic, serotonin and dopamine receptors in an arthritic pain model of rats.