Yonsei medical journal
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Yonsei medical journal · May 2015
Detection of plasma BRAF(V600E) mutation is associated with lung metastasis in papillary thyroid carcinomas.
The BRAF(V600E) mutation represents a novel indicator of the progression and aggressiveness of papillary thyroid carcinoma (PTC). The purpose of this study was to determine the clinical significance of free circulating mutant BRAF(V600E) in predicting the advanced disease of PTC. ⋯ These findings suggest that the BRAF(V600E) mutation can be detected using a PNA clamp real-time PCR in the blood of PTC patients with lung metastasis. Future studies are warranted to determine clinical significance of serum BRAF(V600E) mutation in large prospective studies.
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Yonsei medical journal · May 2015
Randomized Controlled Trial Comparative StudyComparison of ultrasound-guided axillary brachial plexus block techniques: perineural injection versus single or double perivascular infiltration.
We compared three methods of ultrasound-guided axillary brachial plexus block, which were single, and double perivascular (PV) infiltration techniques, and a perineural (PN) injection technique. ⋯ The PV injection technique consisting of a single injection in 12-o'clock position above the axillary artery in addition to a musculocutaneous nerve block is equally effective and less time consuming than the PN technique. Therefore, the PV technique is an alternative method that may be used in busy clinics or for difficult cases.
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Yonsei medical journal · May 2015
Randomized Controlled TrialSparing effects of sufentanil on epidural ropivacaine in elderly patients undergoing transurethral resection of prostate surgery.
This study examined the sparing effect of sufentanil on the median effective concentration (EC₅₀) of epidural ropivacaine in elderly patients undergoing elective transurethral resection of prostate (TURP). ⋯ Administration of 5 μg of epidural sufentanil caused a 37% reduction in the EC₅₀ of epidural ropivacaine in elderly patients who underwent TURP surgery. Thus, sufentanil addition during surgery of TURP can decrease the dose of ropivacaine anesthesia required.
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Yonsei medical journal · May 2015
Comparative StudyEfficacy of percutaneous epidural neuroplasty does not correlate with dural sac cross-sectional area in single level disc disease.
Percutaneous epidural neuroplasty (PEN) is a minimally invasive treatment. The efficacy of PEN has been relatively well investigated; however, the relationship between the clinical effectiveness of PEN and the severity of spinal canal stenosis by disc material has not yet been established. The purpose of this study was to compare clinical outcomes of PEN according to the dural sac cross-sectional area in single level disc disease. ⋯ PEN is an effective procedure in treating single level lumbar disc herniation without affecting dural sac cross-sectional area.
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Yonsei medical journal · May 2015
Randomized Controlled TrialEffect of a sleep aid in analgesia after arthroscopic rotator cuff repair.
The aim of this study was to evaluate the effects and safety of a sleep aid for postoperative analgesia in patients undergoing arthroscopic rotator cuff repair. ⋯ The use of zolpidem for analgesia after arthroscopic rotator cuff repair provided a significant reduction in the need for rescue analgesic without increasing adverse effects. Nevertheless, mean VAS pain scores during the first 5 days after surgery did not differ between the zolpidem group and the control group.