Yonsei medical journal
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Yonsei medical journal · Jun 2023
Multicenter StudySevere Systemic Reactions Following Bee Sting Injuries in Korea.
Most bee sting injuries are benign, although sometimes they can result in life threatening outcomes, such as anaphylaxis and death. The purpose of this study was to investigate the epidemiologic status of bee sting injuries in Korea and to identify risk factors associated with severe systemic reactions (SSRs). ⋯ Our findings emphasize the need for implementing safety policies and education on bee sting-related incidents to protect high-risk groups.
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Junctional adhesion molecule (JAM)-A is an immunoglobulin-like molecule that colocalizes with tight junctions (TJs) in the endothelium and epithelium. It is also found in blood leukocytes and platelets. The biological significance of JAM-A in asthma, as well as its clinical potential as a therapeutic target, are not well understood. The aim of this study was to elucidate the role of JAM-A in a mouse model of asthma, and to determine blood levels of JAM-A in asthmatic patients. ⋯ These results suggest that JAM-A is involved in the pathogenesis of asthma, and may be a marker for asthma.