The Tohoku journal of experimental medicine
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Tohoku J. Exp. Med. · Oct 2011
Randomized Controlled TrialPosterior pericardiotomy reduces the incidence of atrial fibrillation, pericardial effusion, and length of stay in hospital after coronary artery bypasses surgery.
Artrial fibrillation is the most common arrhythmia that occurs after coronary bypass grafting operation with the rate of 30%. Atrial fibrillation is associated with hemodynamic instability, strokes, and prolonged hospital stay. Pericardial effusion is a risk factor for atrial fibrillation after cardiac surgery, and it occurs commonly in the posterior area during the post-operative period. ⋯ Moreover, posterior pericardiotomy was associated with the decreases in the duration of stay in hospital and intensive care unit. In fact, the total hospital costs were lower in the pericardiotomy group. In conclusion, posterior pericardiotomy is an effective and safe technique that reduces early pericardial effusion, atrial fibrillation, length of stay in hospital, and hospital costs after the coronary artery bypasses grafting.
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Tohoku J. Exp. Med. · Dec 2009
Randomized Controlled TrialThe herbal medicine Daikenchuto increases blood flow in the superior mesenteric artery.
Daikenchuto is a traditional herbal medicine that is used for the treatment of cold feeling in the abdomen, while Orengedokuto, also a traditional herbal medicine, is used for treating inflammatory and ulcerative diseases affecting internal organs. However, the effects of these herbal medicines on cardiac output (CO) and intestinal blood flow have never been investigated. This examiner-blinded randomized crossover study intended to clarify the influence of Daikenchuto and Orengedokuto on CO and blood flow volume in the superior mesenteric artery (SMA). ⋯ SMA blood flow volume was significantly increased between 5 and 90 min after administration of Daikenchuto (p < 0.01) compared to the resting state. However, there was no significant change in CO after the administration of either agent. The present study indicates that Daikenchuto increases SMA blood flow volume without increasing CO.
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Tohoku J. Exp. Med. · Feb 2009
Randomized Controlled TrialResponsive measures to prehabilitation in patients undergoing bowel resection surgery.
Surgical patients often show physiological and metabolic distress, muscle weakness, and long hospital stays. Physical conditioning might help recovery. We attempted to identify the most responsive measure of aerobic fitness from a four-week pre-surgical aerobic exercise program (prehabilitation) in patients undergoing major bowel resection. ⋯ There was no change to maximal or submaximal measures in the control group. The distance walked over six minutes improved in both groups (by approximately 30 m), but the effect size and t-statistic were higher in the exercise group. Heart rate and oxygen uptake during submaximal exercise, and peak power output are the most responsive measures to four weeks of prehabilitation in subjects with low initial fitness.
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Tohoku J. Exp. Med. · Oct 2006
Randomized Controlled TrialHemodynamic and anesthetic advantages of dexmedetomidine, an alpha 2-agonist, for surgery in prone position.
The alpha2-agonist dexmedetomidine (Dex), a sedative and analgesic, reduces heart rate (HR) and blood pressure, and has been used in the practice of anesthesia. In this study, we aimed to evaluate the effects of Dex on hemodynamic variables, anesthetic sparing effects, and recovery profiles in patients who underwent surgery in prone position. The prone position itself can cause a decrease in the systemic blood pressure. ⋯ Thus, the use of Dex caused no detrimental effects on the hemodynamic variables in prone position. In addition, Dex decreased pressure response to intubation, and anesthetic and analgesic requirements, shortened recovery times, and decreased postoperative pain level. Dex may be an alternative to currently used adjunctive anesthetic agents in lumbar discectomy operations.
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Tohoku J. Exp. Med. · Jan 2005
Randomized Controlled Trial Comparative Study Clinical TrialSuprascapular nerve block versus steroid injection for non-specific shoulder pain.
Shoulder pain is a common complaint in elder population and may cause an important functional disability. The aim of this study was to compare the effects of suprascapular nerve block with those of steroid injection in patients with non-specific shoulder pain. A total of 60 patients with shoulder pain lasting for more than four weeks were included in this study. ⋯ No method was found to be superior to each other (p >0.05). No complications occurred in suprascapular nerve block in contrary to steroid injection. We suggest that suprascapular nerve block can be considered the preferred treatment for non-specific shoulder pain because of being as effective as steroid injection with rare side effects.