Zentralblatt für Gynäkologie
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Case Reports
[Spontaneous post-partum inhibitor to factor VIII clotting anti- gen--a cause of life-threatening hemorrhage].
Pathologic inhibitors of blood coagulation as cause of acquired haemostatic failure are rare. We report about a 23 years old primigravida with a life-threatening haemorrhage post partum. ⋯ We reacted successfully with cyclophosphamid and cryoprecipitated factor VIII. References to diagnostic and therapy of pathologic clotting factor inhibitors are described.
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In the past decade modern, perioperative short-term antibiotic-prophylaxis has been widely accepted in certain gynecological operations and in caesarean section. Many studies demonstrate the clinical effectiveness. ⋯ The infectious morbidity should be carefully evaluated at every department. The older Cephalosporins (first and second generation) should be used for prophylaxis.