Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
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Zhongguo Zhong Yao Za Zhi · Sep 2013
[Spontaneous reporting system data analysis of parenterally administered Shenmai].
Spontaneous reporting system (SRS) datais currently an important source of monitoring and finding ADRs signals throughout the world. This method can promptly and effectively discover ADR signals, thus preventing and avoiding ADRs effectively. Parenterally administered Shenmai has the functions of benefiting vital energy, nourishing Yin and generating body fluids, and activating the pulse. ⋯ Early warning signs of an ADR are, a feeling of suffocation (difficulty exhaling), anaphylactoid reactions and flushing. Furthermore, relevant relationships between the different factors is analysed by association rules (AR). It is found that there is a close relationship between past history of ADRs, a family history of ADRs and itching.
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Zhongguo Zhong Yao Za Zhi · Sep 2013
[Clinical outcomes of parenterally administered shuxuetong--analysis of hospital information system data].
Hospital information system data of cerebral infaction patients who received parenterally administered Shuxuetong was analyzed. This provided frequency data regarding patients' conditions and related information in order to provide a clinical reference guide. ⋯ Patients with cerebral infarction crowd using parenterally administered Shuxuetong were a mostly elderly population, with an average age of 66. Although generally use was in accordance with indications, dosage, and route of administration, there were however some discrepancies. Therefore, doctors need to pay close attention to guidelines and closely observe patients when using parenterally administered Shuxuetong and to consider both the clinical benefits and risks.
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Undertake analysis of the pragmatic use of Shuxuening injection, in order to understand the drug's characteristics and risks. This will provide the basis for a deeper understanding for risk management. ⋯ Shuxuening injection is primarily used for older patients. Several clinical risk factors have been identified including administering the wrong dose for inappropriate conditions and failure to follow guidelines. Appropriate risk management is required to protect patients.
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Zhongguo Zhong Yao Za Zhi · Sep 2013
[Spontaneous reportintg system data based on shuxuetong injection adverse reactions signal warning analysis].
In this study, January 2009-December 2012 national adverse drug reaction monitoring center Shuxuetong the SRS data for the study, using the reporting rate ratio method and Bayesian belief propagation neural network Shuxuetong ADR warning signal, and balanced use of propensity score methods confounders. The results showed that chills as a possible warning signal. Tip clinical use Shuxuetong injection when, for the elderly, children, liver and kidney dysfunction are more prone to adverse reactions in patients with other special populations, the need to pay attention to the prevention of systemic allergic reactions, in particular the prevention shivering.
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Zhongguo Zhong Yao Za Zhi · Sep 2013
[Pharmacovigilance of parenterally administered salvianolate based on analysis of spontaneous reporting system data].
Spontaneous reporting system (SRS) is currently a basic method to monitor and find adverse drug reactions (ADR) signals used worldwide. This method can promptly and effectively discover ADR signals and is of great significance to effectively prevent and avoid ADRs. Parenterally administered salvianolate has the functions of activating blood circulation and removing stasis. ⋯ The drugs early warning signs were dizziness, headache, nausea, itchiness and rash estimated using PRR. Early warning signs based on BCPNN were dizziness and headache. The ADRs of dizziness and headache are early warning signals associated with the nervous system.