Pain management
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Randomized Controlled Trial
Qualities of Sore Throat Index (QuaSTI): measuring descriptors of sore throat in a randomized, placebo-controlled trial.
Patients with pharyngitis often describe various sensory, affective and evaluative pain qualities. Using an 11-word/phrase index, the Qualities of Sore Throat Index (QuaSTI), we characterized throat symptoms and evaluated changes in a randomized controlled trial (NCT01986361). ⋯ The QuaSTI is a sensitive instrument for measuring therapeutic effects in patients with pharyngitis.
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To compare outcomes of continuous subcutaneous infusion of local anesthetic and epidural analgesia following the Nuss procedure. ⋯ Continuous subcutaneous infusion of local anesthetic could eliminate the need for thoracic epidural for pain management after the Nuss procedure.
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Randomized Controlled Trial Comparative Study
The comparative pharmacokinetics of physical manipulation by crushing of Xtampza® ER compared with OxyContin®.
To further characterize the pharmacokinetics of Xtampza® ER. ⋯ This second pharmacokinetic study demonstrated that Xtampza ER maintains its ER properties after crushing, unlike OxyContin, which failed to retain its ER properties after crushing. ANZCTR registration number: ACTRN12614000613606.