Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns / [Chung-hua cheng hsing shao shang wai k'o tsa chih pien chi wei yüan hui pien chi]
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Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi · Jul 1997
Randomized Controlled Trial Clinical Trial[A clinical study of early enteral feeding to protect the gut function in burned patients].
In order to investigate the effects of early enteral feeding on the gut after burn, 21 cases (mean burn area 45%) were randomly divided into early feeding group (EF group) and delayed feeding group (DF group). The results showed that the levels of plasma endotoxin and MDA in EF group were much lower on PBD 4, 8, 14 than those of DF group (P < 0.05-0.01), and plasma SOD was much lower in DF group on PBD 4, 8 (P < 0.01). The contents of serum gastrin and plasma motilin were obviously increased, and TNF IL-8 much lower in EF group at most time points (P < 0.05-0.01). Therefore, it seems that the early enteral feeding can decrease the level of plasma endotoxin in blood, reduce reperfusion injury of the gut, and blunt the chain reaction of "endotoxin-inflammatory mediator-gut mucosa injury."
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Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi · Jul 1997
[The changes of fibrinolysis in plasma and wounds in rats inflicted with deep partial thickness burns].
We observed the changes in wound histopathology and fibrinolysis of rats with deep partial thickness burns during 10 days after scalding in order to study the relations of early progressive damage of deep partial thickness burn wound and the healing of the wound to fibrinolysis. Using Masson's trichrome stain of collagen, we demonstrated that partial thickness burn wound progressively deteriorated within 72 hours postburn, and epidermal cells on wound edge proliferated, creeping between necrotic and residual collagen by 10th day postburn. ⋯ The analysis of dynamic changes and relations in fibrinolytic parameters revealed that the suppressive factors of fibrinolysis might be enhanced activities of PAI, alpha 2-antiplasmin and antithrombin II after injury. Results suggested that suppression of fibrinolysis might protect fibrin deposited in the wound from lysis and play an important role in early progressive deterioration of deep partial thickness burn and regulation of its healing.
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Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi · Nov 1996
Comparative Study[Evaluation of therapeutic effects of moist burn ointment and betadine ointment in treatment of severe burn].
In order to compare the therapeutic value of moist burn ointment (MBO) and betadine ointment in severe burns, the authors divided 30 patients with burn over 30% TBSA into two groups. In one group MBO was used, and in another group betadine was used. The result showed; 1. ⋯ MBO had little antibacterial effect, wound healing was delayed, and incidences of infection, complication and mortality were higher. At the same time, MBO did not have noticeable effect in inhibiting scar hypertrophy. The authors suggest that MBO must be used with caution in severe burn patients, especially in the southern provinces where the climate is hot and humid.
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Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi · Nov 1996
[Determination of placental alkaline phosphatase (PLAP) for detecting the damages of alveolar type I cells caused by smoke inhalation].
The placental alkaline phosphatase (PLAP) is a marker enzyme of alveolar type I cells. To evaluate the damages of alveolar type I cells and its relations with the development of acute lung injury caused by smoke inhalation, the present study was designed to observe the dynamic changes in PLAP contents in plasma and bronchoalveolar lavage fluid (BALF). Following the induction of smoke inhalation injury in rat, the arterial blood gas levels, lung water volume, total protein and albumin contents in BALF, and PLAP contents in plasma and BALF were determined respectively in normal control and injured animals at 2, 6, 12 and 24 h after injury. ⋯ Both PLAP contents in plasma and BALF also increased dramatically, and there was a significant positive correlation between the changes in the PLAP and the total protein contents in BALF. The pathomorphologically serious structural damage of alveolar type I cells were also found. PLAP may be not only a marker of alveolar type I cells injury, but also interrelated with the permeability increase of alveolar-capillary membrane after smoke inhalation.