Acta chirurgica Hungarica
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Surgical exploration is of prime importance in treating hand infections. In addition, it is essential to apply up-to-date and adequate antibiotic treatment. Authors employed antibiotics during the treatment of hand infections of 65 various aetiologies and types by considering the antibiotic sensitivity spectrum of the most frequent pathogens as also the effective concentration of the antibiotic acting in the inflammatory focus. ⋯ The use of certain antibiotics is recommended in view of the most frequent pathogens of hand infections, of the spectrum of the antibiotic selected by the authors as well as in that of the measured tissue antibiotic concentrations in the dosage used by them. The effective application as well as dosage are also published. Regarding that, in practice, antibiotic treatment should be started according to the nature of the disease without knowing the spectrum of resistance and the pathogen, it is considered important for them to select initially, beside the surgical treatment, an antibiotic which is probably effective and is capable of entering in a sufficient amount the focus of inflammation.
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Acta chirurgica Hungarica · Jan 1989
Case ReportsPacemaker twiddler's syndrome (rotation of the pacemaker around the electrode cable, a rare complication of pacemaker therapy).
Rotation of the pacemaker generator around the electrode cable (i.e. twiddler's syndrome) was observed by the authors in six cases during the implantation of 4250 pacemakers. Twiddler's syndrome developed in three cases following implantation and in three cases after the replacement of the pacemaker. ⋯ For treating twiddler's syndrome, reimplantation was performed, fashioning a small and tight pocket for the device and fixing it by transfixing sutures. After reimplantation, the patients became complaint free, no recurrences occurred.
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Acta chirurgica Hungarica · Jan 1984
Continuous monitoring of gastric movements in rats subjected to restraint.
Gastric motility was recorded continuously by strain gage technique in two groups of animals, subjected to 24 hours' restraint. Ten rats served as control and 10 were pretreated with 100 mg/kg of cimetidine. The electric signals, produced by gastric movements, were recorded by a tape recorder and were then further analysed by a computer. ⋯ It was established that there was no essential difference in the two experimental groups concerning the gastric motility pattern. Brisk gastric movements could be recorded during the whole period of restraint. It may be concluded that increased gastric movements may not play an important role in the pathogenesis of stress-induced mucosal lesions and that cimetidine exerts its anti-ulcer effect via other mechanisms than influencing gastric motility.
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The authors examined the effect of osmium tetroxide (OsO4) on the synovial membrane and cartilage of the rat knee joints by light-, polarization-, and electron microscope. They found that the synovial membrane undergoes severe damage after a 10 min exposure to OsO4. Removing the OsO4 from the joint cavity by perfusion after the 10 min exposure, there was no concomitant damage to the cartilage. Based on experimental results, the authors recommend in human therapy the exposure of the joints to OsO4 for no longer than 10 min and complete removal by exhaustive perfusion.
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Acta chirurgica Hungarica · Jan 1983
Comparative StudyClinical experiences with pipecuronium bromide.
In two groups of patients the neuromuscular and circulatory effects of pipecuronium bromide (Arduan R), a new steroid type muscle relaxant were compared with those of pancuronium during balanced anaesthesia. Pipecuronium (n = 18) was found to be about 20% more potent than pancuronium (n = 20). ⋯ The onset, clinical relaxation time (clinical duration), recovery and the reversibility of the neuromuscular effects of the two agents in equipotent doses were similar. No cardiovascular or other side effects were observed with the use of pipecuronium.