Acta anaesthesiologica Sinica
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Acta Anaesthesiol. Sin. · Dec 1997
Randomized Controlled Trial Comparative Study Clinical TrialThe analgesic effect of PCA buprenorphine in Taiwan's gynecologic patients.
The aim of this study was to evaluate the analgesic effect of PCA buprenorphine (intravenous) on postoperative pain in gynecologic patients of Taiwan and the potency ratio of buprenorphine versus morphine, a commonly used potent analgesic. ⋯ We found that PCA buprenorphine (intravenous) could be effective in the treatment of postoperative pain in the gynecologic patients in Taiwan and the potency ratio of buprenorphine versus morphine appeared to be 24:1.
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Acta Anaesthesiol. Sin. · Dec 1997
Randomized Controlled Trial Clinical TrialComparison of intravenous retention of fentanyl and lidocaine on local analgesia in propofol injection pain.
With a tourniquet on arm for arresting venous blood flow, we evaluated the efficacy of intravenous (i.v.) retention of fentanyl and lidocaine in reducing the pain on i.v. propofol injection during general anesthesia. ⋯ Intravenous retention of fentanyl 150 micrograms, although less effective than that of lidocaine (p < 0.001), showed local analgesic effect in reducing the pain on propofol injection. The hypothetic mechanisms of action were speculated.
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Acta Anaesthesiol. Sin. · Sep 1997
Randomized Controlled Trial Comparative Study Clinical TrialIntermittent bolus versus patient-controlled epidural morphine for postoperative analgesia.
Patient-controlled epidural analgesia (PCEA) is a technique that combines the flexibility and convenience of PCA with the intrinsic analgesic efficacy of epidurally administered opioids. The aim of this study is to compare the analgesic and side effects of intermittent bolus injections of epidural morphine with PCEA using morphine during the first 24 h after elective low abdominal surgery. ⋯ PCEA with morphine decreases morphine consumption and with less adverse effects than intermittent bolus of epidural morphine. PCEA with morphine is an acceptable alternative to epidural morphine after low abdominal surgery.
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Acta Anaesthesiol. Sin. · Sep 1997
Randomized Controlled Trial Comparative Study Clinical TrialComparison of neuromuscular action of rocuronium, a new steroidal non-depolarizing agent, with vecuronium.
Rocuronium is a new nondepolarizing muscle relaxant. It features a rapid onset and lack of histamine release: It has an intermediate onset of action as vecuronium. The purpose of this study was to compare the neuromuscular action and condition of intubation after a bolus dose of rocuronium or vecuronium (2 x ED90). We also compared the duration of relaxation after intubation and maintenance doses of each drug. ⋯ We conclude that rocuronium provides a more rapid onset of action than that of vecuronium. Rocuronium is an intermediate-acting muscle relaxant as vecuronium with good to excellent intubation condition. It may be an useful alternative to vecuronium for rapid tracheal intubation.
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Acta Anaesthesiol. Sin. · Jun 1997
Randomized Controlled Trial Comparative Study Clinical TrialComparison of epidural butorphanol plus clonidine with butorphanol alone for postoperative pain relief.
Epidural butorphanol has been shown to produce effective analgesia with less side effects than that of morphine but relatively short duration. Clonidine, an alpha 2-adrenergic agonist, has been reported to provide [corrected] pain relief by epidural administration. Furthermore, epidural clonidine has been shown to potentiate the analgesic effect of epidural morphine. The present study was undertaken to evaluate the analgesic and side effects of epidural administration (Ep) of butorphanol and clonidine. ⋯ Our study showed that the addition of clonidine to epidural butorphanol did not enhance its analgesic effect in any significant manner nor did it reduce the adverse effects. This combination does not seem to offer any advantage for clinical use.