Acta anaesthesiologica Sinica
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Acta Anaesthesiol. Sin. · Jun 1997
Randomized Controlled Trial Clinical TrialThe preemptive effect of pre-incisional bupivacaine infiltration on postoperative analgesia following lower abdominal surgery under epidural anesthesia.
In attempts to reduce central sensitization after tissue injury, the concept of preemptive analgesia has evolved. The aim of the present study was to evaluate the preemptive effect of pre-incisional infiltration of the surgical area with bupivacaine on pain following lower abdominal surgery under epidural anesthesia. ⋯ The results indicate that pre-incisional infiltration of surgical area with bupivacaine markedly decreases the intensity of pain following lower abdominal surgery under epidural anesthesia.
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Acta Anaesthesiol. Sin. · Jun 1997
Randomized Controlled Trial Comparative Study Clinical TrialComparison of epidural butorphanol plus clonidine with butorphanol alone for postoperative pain relief.
Epidural butorphanol has been shown to produce effective analgesia with less side effects than that of morphine but relatively short duration. Clonidine, an alpha 2-adrenergic agonist, has been reported to provide [corrected] pain relief by epidural administration. Furthermore, epidural clonidine has been shown to potentiate the analgesic effect of epidural morphine. The present study was undertaken to evaluate the analgesic and side effects of epidural administration (Ep) of butorphanol and clonidine. ⋯ Our study showed that the addition of clonidine to epidural butorphanol did not enhance its analgesic effect in any significant manner nor did it reduce the adverse effects. This combination does not seem to offer any advantage for clinical use.
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Acta Anaesthesiol. Sin. · Mar 1997
Randomized Controlled Trial Comparative Study Clinical TrialComparison of oral controlled-release morphine with transdermal fentanyl in terminal cancer pain.
Controlled-release morphine (MST) given twice daily provides a simpler and more convenient treatment regimen than 4-hourly opioid administration for the control of cancer pain. Recently, a new formulation of transdermal fentanyl (TDF) has been developed which provides a new route for the treatment of cancer pain. The present study was designed to compare the analgesic efficacy, safety and adverse effects of MST and TDF in the management of chronic cancer pain. ⋯ These results suggest that TDF and MSt are safe and effective analgesics for the management of chronic cancer pain. However, TDF provides a simpler and more convenient treatment for those patients with severe nausea, vomiting or dysphagia.
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Acta Anaesthesiol. Sin. · Mar 1997
Randomized Controlled Trial Comparative Study Clinical TrialComparison of sevoflurane with halothane in pediatric ambulatory anesthesia: an experience in Taiwan.
Sevoflurane, with blood/gas partition coefficient of 0.69 and MAC of 1.76 is a fast acting, potent inhalation anesthetic. Its suitability and safety for pediatric ambulatory anesthesia were assessed and compared with that of halothane. ⋯ The results strongly suggest that sevoflurane is preferable to halothane for pediatric ambulatory anesthesia.
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Acta Anaesthesiol. Sin. · Mar 1997
Randomized Controlled Trial Clinical TrialThe incidence of post dural puncture headache in Taiwanese patients undergoing cesarean section.
In Taiwan, there was only a retrospective study about the post-dural puncture headache (PDPH) resulting from spinal anesthesia for cesarean section (C/S), but it did not mention the relationship between the incidence of PDPH and the number of dural punctures, as well as between the gauge of spinal needle. Therefore, we designed a prospective study to investigate if the spinal needles for smaller gauges could decrease the incidence of PDPH in anesthesia for C/S. ⋯ It appears that the incidence of PDPH does not differ between Taiwanese and Westerners. Pregnancy may be the key factor contributing to higher incidence of PDPH. The 26-gauge spinal needle may lower the incidence of PDPH to a greatest extent in C/S patients, although in comparison with 24- and 25-gauge needles the difference is not statistically significant.