The American journal of otology
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To test the relative dose-related cochlear and vestibular ototoxicity produced by transtympanically injected gentamicin in the Mongolian gerbil. ⋯ Our results suggest that in the gerbil, gentamicin is ototoxic but not selectively vestibulotoxic. In general, increasing the number of transtympanic injections increases the damage to sensory hair cells in both the posterior crista and the cochlea. A variation in interanimal susceptibility to ototoxic effects exists, but the amount of damage is consistent in both cochlear and vestibular hair cells from the same animal.
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The study aimed to present clinical, radiographic, and operative findings in cases of recurrent facial neuromas and discuss changes in demographics of primary facial neuromas since 1986. ⋯ Improved imaging techniques have documented an increased incidence of primary facial neuromas medial to the geniculate ganglion. Clinical suspicion, histologic confirmation of tumor-free margins, interspecialty cooperation in tumor resection, and routine follow-up imaging with magnetic resonance imaging are suggested to minimize recurrent facial neuromas.
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Comparative Study
Comparison of response amplitude versus stimulation threshold in predicting early postoperative facial nerve function after acoustic neuroma resection.
This study aimed to better predict the early postoperative facial nerve (FN) function after acoustic neuroma (AN) resection. ⋯ The use of FN threshold and amplitude together is superior to threshold alone as a predictor of early postoperative FN function.
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Electrical stimulation of the cochlea at high rates induces significant adaptation of the auditory nerve. ⋯ The decrease of the WAVE I amplitude in response to high-rate pulsatile stimulation reflects an adaptation of the auditory nerve due, at least in part, to the refractory period of auditory nerve fibers.