Journal of wound care
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Journal of wound care · Jul 2007
Randomized Controlled Trial Comparative StudyEffects of honey and sugar dressings on wound healing.
To investigate whether there is a difference between the efficacy of honey and sugar as wound dressings. ⋯ Honey appears to be more effective than sugar in reducing bacterial contamination and promoting wound healing, and slightly less painful than sugar during dressing changes and motion.
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Journal of wound care · Mar 2007
Randomized Controlled TrialOral transmucosal fentanyl citrate versus placebo for painful dressing changes: a crossover trial.
Fentanyl is a potent opioid that is well absorbed via the oral mucosa. It can be given as an oral lozenge. The onset of analgesia is rapid and matches the pain profile observed at dressing changes. ⋯ Compared with placebo, OTFC improved analgesia during painful dressing changes without an increase in side-effects.
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Journal of wound care · Mar 2006
Randomized Controlled Trial Comparative StudyHoney dressing versus paraffin tulle gras following toenail surgery.
Anecdotal reports suggest that certain honey dressings have a positive effect on wound healing. However, there is limited empirical evidence supporting its use. This double-blind randomised controlled trial investigated the effect of a honey dressing on wound healing following toenail surgery with matrix phenolisation. ⋯ The results suggest that patients may benefit more from paraffin tulle gras dressings than honey dressings following partial toenail avulsion. No statistically significant difference was found for healing times after total toenail avulsion, although the marginal benefit of the honey dressing on these healing times warrants further investigation.
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Journal of wound care · Nov 2001
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialIs tap water a safe alternative to normal saline for wound irrigation in the community setting?
This double-blind randomised controlled trial compared the effects of tap water and normal saline on the healing and infection rates of acute and chronic wounds. ⋯ Although the small sample size is a limitation of this study, the researchers conclude that drinkable tap water appears to provide a safe alternative to normal saline for wound cleansing and may be preferred by some patients.
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Journal of wound care · Jan 2001
Randomized Controlled Trial Multicenter Study Clinical TrialUsing a topical anaesthetic cream to reduce pain during sharp debridement of chronic leg ulcers.
This multicentre, double-blind, placebo-controlled, parallel-group study assessed the efficacy and safety of using Emla (lignocaine/prilocaine) anaesthetic cream to achieve pain control during sharp debridement of chronic leg ulcers of arterial, venous or arteriovenous aetiology. A total of 101 patients (51 Emla, 50 placebo), aged 29-99 years, who had experienced pain associated with previous debridement were included. Patients with an amide anaesthetic allergy, anaesthetic diabetic ulcers, or ulcers > 50 cm2 were excluded. ⋯ The corresponding investigator values in the two groups were 20 mm and 49.5 mm, respectively (p = 0.004). Local reactions were mainly transient and mild, and were observed in roughly the same percentage of placebo and Emla-treated patients. After a 30-minute application Emla cream significantly reduced the pain of debridement compared with the placebo.