Deutsche medizinische Wochenschrift
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Dtsch. Med. Wochenschr. · Jul 1999
Case Reports[Extra-intestinal manifestations and complications in chronic active ulcerative colitis in childhood and adolescence].
A 18-year-old girl suffered from chronic active ulcerative colitis for ten years with growth retardation, primary amenorrhoea and osteopenia, so that total colectomy had been discussed as a possible treatment option. However, clinical remission was reached using a medication with budesonide (9 mg), mesalazine (3 g) and azathioprine (100 mg) when a painful ulcer occurred at the right lower leg. ⋯ Drug therapy with azathioprine can be regarded as a treatment option in pediatric patients with chronic active inflammatory bowel disease. It can be concluded from this case report that faced with controversial therapeutic options in adolescent patients the decision mainly depends on the clinical experience of the physician than on the results of controlled clinical trials.
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Dtsch. Med. Wochenschr. · May 1999
Multicenter Study Comparative Study Clinical Trial[Can diagnostic scoring systems help decision making in primary care of patients with suspected acute appendicitis?].
To assess two recently developed scoring systems with respect to making or excluding the diagnosis of acute appendicitis. ⋯ Both diagnostic scoring systems are better for excluding than correctly diagnosing AA; the decision to exclude could be made with a high degree of accuracy. Either scoring system may therefore be used in primary care of patients suspected of AA to help decide on referral to hospital.