Deutsche medizinische Wochenschrift
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Adverse effects of drug therapy may induce a wide variety of bronchopulmonary disorders. The spectrum of drug induced lung and bronchial diseases include simple cough, bronchial obstruction, and obstructive bronchiolitis. Lung parenchyma may be affected by alveolitis/pneumonitis or lung fibrosis. ⋯ Reexposure is rarely indicated. Strict elimination of the responsible drugs is the most important therapeutic measure. Additional drug therapy, mostly with glucocorticosteroids, may be indicated.
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Delirium occurs in 20 - 50 % of hospitalized elderly patients. An age > 65 years is one of the factors predisposing to the development of delirium, which is a common syndrome in geriatric medicine. Two clinical guidelines on this condition were published in 2010: NICE clinical guideline 103, "Delirium: diagnosis, prevention, management" and the German guideline "S3-Leitlinie Analgesie, Sedierung und Delirmanagement in der Intensivmedizin". The article gives an overview of new aspects of delirium in the clinical context.
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Dtsch. Med. Wochenschr. · Mar 2011
Review[Sleep disordered breathing and cardiac arrhythmias: mechanisms, interactions, and clinical relevance].
In patients with cardiac disease growing interests have been centered on concomitant co-morbidities such as sleep disordered breathing (SDB). Obstructive sleep apnoea (OSA) as well as Cheyne-Stokes Respiration (CSR) have been recognized as relevant co-morbidities that are highly prevalent and associated with an impaired prognosis. ⋯ Sufficiently suppressing SDB by adequate therapies seems to ameliorate its arrhythmogenic impact. However, especially for CSR data from randomized, controlled trial are urgently awaited to definitely answer this question.