Zhurnal mikrobiologii, epidemiologii, i immunobiologii
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Zh. Mikrobiol. Epidemiol. Immunobiol. · May 1983
Comparative Study[IgG subclasses in chronic brucellosis patients].
The data on the levels of immunoglobulins belonging to the main classes (IgA, IgM, IgG) and IgG subclasses (IgG1, IgG2, IgG3, IgG4) in the sera of 52 patients with chronic brucellosis lasting 1-10 years are presented; in 10 of these patients immunoglobulin levels before and after vaccinal therapy are given. The blood sera of chronic brucellosis patients were found to contain IgG of 4 subclasses, the concentration of IgG1, IgG2 and IgG4 being, on the average, normal and the concentration of IgG3, elevated. A certain correlation between the increase of the IgG level and the presence of 2-mercaptoethanol-resistant specific antibodies was observed. After brucellosis patients received the injections of therapeutic vaccine, their levels of IgG and IgG1 increased, while the concentration of IgG3 decreased and that of IgG2 and IgG4 remained unchanged.
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Zh. Mikrobiol. Epidemiol. Immunobiol. · Sep 1998
Clinical Trial[Staphylococcal persistence factors in the prognostication of the course of pyo-inflammatory diseases].
The role of Staphylococcus aureus persistence factors as the most informative signs of bacteria in the determination of the specific features of purulent inflammatory diseases has been established. The model for the prognostication of the character of the course of the purulent inflammatory process, induced by staphylococci, with due regard to the complex of their persistence factors has been created.
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Zh. Mikrobiol. Epidemiol. Immunobiol. · Jul 2011
Clinical Trial[Vaccination against influenza A (H1N1) in pregnancy].
Evaluation of alterations of immune response regulation and possible risk of antenatal development of fetus in postvaccination period in pregnant women immunized against influenza A (H1N1). ⋯ Vaccination of pregnant women against influenza A (H1N1) by Russian subunit formulation (MonoGrippol plus) showed reactogenicity comparable to control group by the level of influence on general metabolic and immunologic homeostasis and on the course of pregnancy, which is an evidence of its safety.
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Zh. Mikrobiol. Epidemiol. Immunobiol. · Nov 2014
[Prevalence of cytotoxicity effectors in nosocomial Pseudomonas Aeruginosa strains].
Analysis of occurrence of the third type secretory system (TTSS) effectors in clinical P. aeruginosa strains. ⋯ A significant association between exoU and blaVIM-2 could be explained by clonal prevalence of P. aeruginosa ST235 VIM-2, circulation of those is noted on all the territory of Russia. As a rule, ExoU is produced by highly virulent poly-antibiotic resistant hospital isolates that determine unfavorable outcomes of pseudomonas infection.