Pain medicine : the official journal of the American Academy of Pain Medicine
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Clinical Trial
Combination therapy with flupirtine and opioid: open-label case series in the treatment of neuropathic pain associated with cancer.
This study is a case series that was designed to provide data on the efficacy and the incidence and duration of adverse effects of flupirtine in the treatment of cancer-related neuropathic pain. ⋯ These results in humans follow animal studies that suggest a role for flupirtine in the treatment of neuropathic pain. This short duration open-label study in 10 subjects suggests that flupirtine may be useful in the treatment of neuropathic pain when used in combination with opioids.
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To assess the influence of fear avoidance beliefs (FAB) and catastrophizing on low back pain (LBP)-related disability in Spanish community dwelling retirees. ⋯ In Spanish community dwelling retirees, the influence of FAB and catastrophizing on LBP-related disability is clinically small.
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Multicenter Study Clinical Trial
Titration with oxymorphone extended release to achieve effective long-term pain relief and improve tolerability in opioid-naive patients with moderate to severe pain.
Assess the effectiveness and tolerability of a program of gradual dose titration with oxymorphone extended release (ER) for treatment of moderate to severe chronic pain in opioid-naive patients. ⋯ Oxymorphone ER provided effective pain relief from moderate to severe chronic pain in opioid-naive patients. Gradual titration was well tolerated, with a low rate of discontinuations caused by AEs.
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Randomized Controlled Trial
The ability of single site, single depth sacral lateral branch blocks to anesthetize the sacroiliac joint complex.
To determine the physiologic effectiveness of single site, single depth sacral lateral branch injections. ⋯ Anatomic limitations exist with single site, single depth sacral lateral branch injections rendering them physiologically ineffective on a consistent basis.
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Randomized Controlled Trial
Facial pain: a possible therapy with stellate ganglion block.
The goal of the present study is to verify the efficacy of stellate ganglion block (SGB) in the treatment of facial pain that can be found in different pathological syndromes, and also to examine whether the efficacy is dependent upon when this therapy is administered. ⋯ Our results indicate that patients must be treated with SGB therapy precociously to receive its full benefits.