Pain medicine : the official journal of the American Academy of Pain Medicine
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Studies have shown a relationship between insulin resistance (IR) and migraine that is more evident in some migraineurs. Long-term use of various drugs and increased risk of diverse side effects is an unavoidable reality in this population of patients. Thus, in this study, we aimed to investigate factors associated with IR in migraine and the impact of chronic usage of various drugs, which might play a part in development of IR. ⋯ Our study demonstrates an association between metoclopramide and NSAID treatments and IR in migraine.
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To describe the development of a virtual reality (VR) treatment for phantom limb pain (PLP) and phantom sensations and provide feasibility data from testing the treatment in a population of veterans. ⋯ This feasibility study of a novel VR intervention for PLP was practical and was associated with significant reductions in PLP intensity and phantom sensations. Our findings support continued research in VR-based treatments in PLP, with a need for direct comparisons between VR and more established PLP treatments.
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Intrathecal (IT) drug delivery has shown its efficiency in treating refractory cancer pain, but switching opioids from the systemic to the intrathecal route is a challenging phase. Moreover, associations are widely used and recommended. Few data deal with the initial dosage of each drug. Analyzing conversion factors and initial dosages used in intrathecal therapy seems essential to decreasing the length of titration and to delivering quick pain relief to patients. ⋯ Local anesthetic:morphine ratio should be considered when starting IDDS treatment. EaPR during the IT analgesia titration phase was associated with better pain relief and outcomes in patients with refractory cancer-related pain.
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Background Research suggests that colors may have an effect on human behavior, cognition, and emotions; however, little is known about their influence on pain perception. The aim of these two studies was to investigate whether colors have an impact on pain perception and to find the mechanism that underlies the influence of colors on pain. Methods In both studies, participants received electrocutaneous pain stimuli of the same intensity preceded by one of six colors (red, green, orange, blue, pink, or yellow) or a blank slide, which served as a control condition. ⋯ Particularly, participants rated pain stimuli preceded by red as being more painful compared with pain stimuli preceded by other colors, especially green and blue. Conclusions It is concluded that colors have an impact on pain perception. Our results have important implications for the color lights paradigm applied in studies on placebo effects.