Pain medicine : the official journal of the American Academy of Pain Medicine
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Pain Med
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This is a structured, evidence-based review of all available studies on the coexistence of fatigue and pain. ⋯ Based on the above results, it was concluded that there is an association between fatigue and pain and that there may be an etiological relationship between pain and fatigue. Pain physicians and other pain treatment professionals should be aware of the high prevalence of fatigue in pain patients. In addition, future research might investigate possible mechanisms for the relationship between pain and fatigue.