São Paulo medical journal = Revista paulista de medicina
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The role of transient obstructive cholestasis on liver histology remains undetermined. ⋯ Transient cholestasis was associated with significant histopathological changes, even after its resolution. Longer duration of obstruction correlated with greater severity of histopathological changes, especially cholestasis and ductular proliferation. This emphasizes the need for early treatment of obstructive cholestasis.
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Heart failure in Brazil is a major public health problem and, even with advances in treatment, it still presents high morbidity and mortality. As a treatment option, mechanical circulatory assist devices (MCADs) have greatly increased in importance over the last decade. ⋯ The decision to implant a MCAD should be individualized, as patient profiles do not always match the indications in the guidelines and protocols. In this study, clinical discussion of the case among the medical and multi-professional teams was essential in order to be able to successfully reverse the patient's severe clinical condition without sequelae, through using a CentriMag implant.
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The COVID-19 pandemic may be having many psychological impacts on people, at both an individual and a community level. ⋯ The lower the weekly frequency of physical activity during the period of social distancing was, the greater the chances of having stress levels were, especially for women.
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Critical diseases usually cause hypercortisolemia via activation of the hypothalamic-pituitary-adrenal axis. ⋯ Very high cortisol levels are associated with severe illness and increased risk of death, among COVID-19 patients in the ICU.