The journal of pain : official journal of the American Pain Society
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Many studies have demonstrated a link between experiences of physical pain and those of social rejection, both of which can trigger cognitive processes involved in detecting, orienting toward, or reacting to potentially threatening events. This study tested the hypothesis that healthy individuals who are more sensitive to physical pain are also more sensitive to social rejection. We recruited participants with high or low pain-sensitivity (HPS and LPS), as assessed by scores on a pain-sensitivity questionnaire and confirmed by experimental pain-sensitivity assessment. ⋯ Altogether, these results supported the idea of shared sensitivity in detecting potentially physical and social threats in the environment. PERSPECTIVES: This study showed the greater emotional reactions and early-latency δ/θ-oscillations in response to social evaluation among healthy individuals with high pain sensitivity. It supports the idea of shared sensitivity to physical pain and social evaluation, which could be governed by a common system for detecting and monitoring potentially environmental threats.
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Use of cannabis to alleviate headache and migraine is relatively common, yet research on its effectiveness remains sparse. We sought to determine whether inhalation of cannabis decreases headache and migraine ratings as well as whether gender, type of cannabis (concentrate vs flower), delta-9-tetrahydrocannabinol, cannabidiol, or dose contribute to changes in these ratings. Finally, we explored evidence for tolerance to these effects. ⋯ Further, there was evidence of tolerance to these effects. PERSPECTIVE: Inhaled cannabis reduces self-reported headache and migraine severity by approximately 50%. However, its effectiveness appears to diminish across time and patients appear to use larger doses across time, suggesting tolerance to these effects may develop with continued use.
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The aim of the study reported in this paper is to investigate the effect of slow-deep breathing (SDB) on self-reported pain, heart rate variability, and baroreflex sensitivity (BRS). These effects are examined in 3 separate experiments, each using a different phasic pain modality. For each experiment, different subjects were recruited. ⋯ Although SDB significantly increased baroreflex sensitivity and heart rate variability, self-reported pain did not differ between breathing conditions, regardless of pain modality. Other potential mechanisms or components should be considered such as behavioral modulators including relaxation and treatment expectation. PERSPECTIVE: Merely slowing down the breathing frequency to .1 Hz is not sufficient to induce hypoalgesia, despite the significant physiological effects associated with SDB compared to spontaneous breathing.
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Pediatric pain assessment in the hospital traditionally involves the patient's self-report of pain intensity using a numeric rating scale, which does not capture the complexity of the pain experience. No valid, comprehensive measure of pain in hospitalized youth exists. This study was designed to develop and conduct initial psychometric testing of the Pediatric American Pain Society Patient Outcomes Questionnaire (Pediatric APS-POQ), a comprehensive patient-reported measure of pain and pain outcomes in hospitalized youth. ⋯ Additional research is needed to further support the reliability and validity of this measure in diverse clinical populations. PERSPECTIVE: To reduce the impact of pain on hospitalized youth, pediatric pain assessment must move beyond ratings of pain intensity. The Pediatric APS-POQ provides a brief but comprehensive assessment of pain and pain outcomes in hospitalized children and adolescents, which will allow for greater individualization in hospital-based pain management and quality improvement purposes.