Developmental medicine and child neurology
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Dev Med Child Neurol · Apr 2012
Bilateral alterations in somatosensory cortical processing in hemiplegic cerebral palsy.
In individuals with cerebral palsy (CP), cerebral insults during early development may induce profound reorganization of the motor representation. This study determined the extent of alterations in cortical somatosensory functions in adolescents with hemiplegic CP with subcortical brain lesions. ⋯ In hemiplegic CP, modification of the somatosensory cortical network extends beyond what would be expected based on the unilateral symptoms and the anatomical lesion. Further understanding of the functional alterations in the sensorimotor networks may aid in developing more precisely designed rehabilitation strategies.
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Dev Med Child Neurol · Mar 2012
Safety and efficacy of flunarizine in childhood migraine: 11 years' experience, with emphasis on its effect in hemiplegic migraine.
The aim of this study was to report a single-centre experience of flunarizine in childhood migraine with focus on safety and efficacy. ⋯ In our cohort of children with migraine, flunarizine appears to be more effective in the hemiplegic migraine group. Adverse effects were seen in one-fifth of the individuals, leading to discontinuation in 18%.
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Dev Med Child Neurol · Dec 2011
ReviewCognitive and psychiatric phenotypes of movement disorders in children: a systematic review.
The cognitive and psychiatric aspects of adult movement disorders are well established, but specific behavioural profiles for paediatric movement disorders have not been delineated. Knowledge of non-motor phenotypes may guide treatment and determine which symptoms are suggestive of a specific movement disorder and which indicate medication effects. ⋯ Although the literature in non-motor phenomena is still emerging, recognition of salient cognitive and psychiatric phenomena may facilitate management of paediatric movement disorders.