Current neurology and neuroscience reports
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Patients with large hemispheric strokes frequently develop neurologic deterioration secondary to cerebral edema. Regardless of the medical and surgical management of cerebral edema, there is high morbidity and mortality. This article reviews the clinical and radiographic features of large hemispheric strokes and examines the various therapeutic options for management of cerebral edema.
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Traumatic brain injury often affects people in their most productive years, inflicting a significant burden on families and society. The advances in modern critical care have improved survival of patients; thus more patients live after traumatic brain injury, which raises an important issue about their neurologic outcome. ⋯ In this review, we try to bring information from different sources to show new approaches to achieve that goal. Some of the techniques employed are investigational and some are waiting to find broader application in intensive care units across the country.
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The surgical treatment of epilepsy is expanding in an exciting and unprecedented way. This review highlights some of the recent advances in neuroimaging that have improved epilepsy surgery. In addition, novel therapies currently being evaluated in clinical trials, including gamma knife radiosurgery, deep brain stimulation, and responsive stimulation, are discussed. Further surgical developments that will be ready for human application in the near future are highlighted.
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Throughout the past decade, there has been a marked increase in surgical therapies, primarily deep brain stimulation (DBS), for the treatment of advanced Parkinson's disease (PD). DBS of the thalamus has been shown to be effective in reducing parkinsonian tremor; however, it is not the treatment of choice for PD given the progression of other symptoms such as rigidity and bradykinesia. ⋯ Complications associated with DBS are related to the experience of the surgical center. Referring physicians and patients should be aware of the number of surgical procedures and complication rates of any prospective surgical center.
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Curr Neurol Neurosci Rep · Mar 2004
Randomized Controlled Trial Clinical TrialPreradiation chemotherapy versus radiotherapy alone for nonmetastatic medulloblastoma.